ArticleThe Australian & New Zealand journal of obstetrics & gynaecology2026
Respiratory Quotient During Pregnancy and the Influence of Macronutrient Intake, Energy Balance and Maternal Fat Mass: An Exploratory Study.
Article in The Australian & New Zealand journal of obstetrics & gynaecology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
introductionMaternal metabolism shifts during pregnancy to support foetal growth and development. Respiratory quotient (RQ) provides insight into the relative contributions of carbohydrate and fat to energy metabolism and is influenced by factors including individual macronutrient intake, energy balance, and fat mass. This study aimed to assess the associations between dietary intake, energy balance, and maternal fat mass with RQ and substrate oxidation in pregnant women.
methodsPregnant women in their first trimester were included. At each trimester (First: 8-13 weeks'; Second: 23-25 weeks'; Third: 34-37 weeks'), macronutrient intake was assessed using a 3-day weighed food diary, with RQ and substrate oxidation measured using indirect calorimetry. Maternal fat mass was measured using bioelectrical impedance analysis.
resultsTwenty-seven women were included. The mean (SD) age of women was 33.3 (5.1) years and mean (SD) pre-pregnancy BMI was 26.4 (5.0) kg/m
conclusionStable macronutrient intake may influence RQ and substrate oxidation. Larger, adequately powered studies are needed to determine whether more pronounced dietary or body composition changes alter substrate oxidation during pregnancy.
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