ArticleOpen forum infectious diseases2026
Delayed Seasonality but Consistent Age Burden: RSV Epidemiology Pre-, During, and Post-COVID-19 Pandemic on the Kenyan Coast (2008-2026).
Article in Open forum infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: The COVID-19 pandemic and associated nonpharmaceutical interventions disrupted the established epidemiological patterns of many endemic respiratory viruses globally. However, its impact on respiratory syncytial virus (RSV) epidemiology in sub-Saharan Africa is understudied. Methods: We analyzed data from a continuous hospital-based pediatric pneumonia surveillance program in coastal Kenya January 2008-June 2026. Children ≤5 years, admitted with World Health Organization-defined syndromic severe or very severe pneumonia were tested for RSV using quantitative reverse transcriptase polymerase chain reaction. The period was stratified into prepandemic (January 2008-March 2020), during pandemic (March 2020-May 2023), and postpandemic (May 2023-June 2026). Multivariable logistic regression evaluated clinical and demographic shifts across periods. Results: Among 10 374 tested children, 2442 (23.5%) were RSV positive. Positivity declined from 25.3% (1919/7585) prepandemic to 18.3% (235/1282) during the pandemic and 19.1% (288/1507) postpandemic. Overall median age of RSV-positive patients remained statistically consistent across all periods (4.3 vs 3.7 vs 3.1 months; Conclusions: Despite a repeated 1- to 2-month delay of RSV season onsets on the Kenyan coast and minor clinical symptoms shifts, the core demographic patterns remained stable. The persisting severe RSV disease in <6-month-olds highlights this population for RSV interventions.
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