Evidence map›Paper›PMID 42872192›Full record

ArticleCanadian liver journal2026

Quality of life and self-reported stigma following hepatitis B surface antigen loss: A multi-site study by the Canadian Hepatitis B Network.

Jordyn Vienneau, Hin Hin Ko, Curtis L Cooper, Karen E Doucette, Magdy Elkashab, Alnoor Ramji, Edward Tam, Scott K Fung, Pam Crotty, Carla S Coffin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Canadian liver journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jordyn VienneauCumming School of Medicine, Snyder Institute, University of Calgary, Calgary, Alberta, Canada.
Hin Hin KoFaculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Curtis L CooperOttawa Hospital Research Institute, University of Ottawa, Ottawa, Ontario, Canada.
Karen E DoucetteFaculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
Magdy ElkashabToronto Liver Centre, Toronto, Ontario, Canada.
Alnoor RamjiFaculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Edward TamFaculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Scott K FungDepartment of Medicine, University of Toronto, Toronto, Ontario, Canada.
Pam CrottyCumming School of Medicine, Snyder Institute, University of Calgary, Calgary, Alberta, Canada.
Carla S CoffinCumming School of Medicine, Snyder Institute, University of Calgary, Calgary, Alberta, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Chronic hepatitis B (CHB) imposes adverse health outcomes but may also cause psychosocial and quality-of-life (QOL) challenges. Hepatitis B surface antigen (HBsAg) loss, whether spontaneous or due to treatment (ie, a functional cure), is associated with improved clinical outcomes, but the impact of HBsAg clearance on patient-reported outcome measures (PROMs) is poorly understood. Methods: Two surveys (hepatitis B self-stigma and hepatitis B-related QOL [HBQOL]) were administered to adults with a history of CHB with documented HBsAg clearance from six Canadian hepatology clinics. Results: Eighty-four participants were enrolled (median age: 60 years; 53.6% male). Nearly three quarters (72.6%) of patients reported never feeling self-stigma. HBQOL scores improved across all six domains ( Conclusions: HBsAg loss was associated with significant improvements in patient-reported stigma and QOL. These findings highlight the importance of incorporating PROMs into hepatitis B virus clinical care to better capture treatment experiences.

Indexed as

functional curequalitativesurvey

Identifiers

PMID42872192
PMCPMC13661165

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.