Evidence map›Paper›PMID 42872124›Full record

ArticleMedComm2026

Integrated Multi-Time-Point

Minyi He, Huiting Yang, Yunxing Shi, Rongqin Zhang, Taixuan Wan, Xiaolin Pang, Zhanwen Zhang, Liang Huang

Registry-linked trialAbstract read
In one paragraph

Article in MedComm, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06608537 (A Single-center, Single-arm Phase II Clinical Study Based on FAPI-PET/CT Technology to Predict Pathological Complete Response After Neoadjuvant Chemoradiotherapy for MSS Rectal Cancer), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06608537 phase2completednot on this map

A Single-center, Single-arm Phase II Clinical Study Based on FAPI-PET/CT Technology to Predict Pathological Complete Response After Neoadjuvant Chemoradiotherapy for MSS Rectal Cancer

TypeinterventionalSponsorSun Yat-sen UniversityRan2024 to 2025Enrolled52ConditionsRectal CancerArmsneoadjuvant SCRT followed by Sintilimab plus CAPOX
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Minyi He *Department of General Surgery (Colorectal Surgery), The Sixth Affiliated Hospital Sun Yat-sen University Guangzhou China.ORCID https://orcid.org/0009-0004-8009-7371
Huiting Yang *Biomedical Innovation Center, The Sixth Affiliated Hospital Sun Yat-sen University Guangzhou China.
Yunxing Shi *Department of General Surgery (Colorectal Surgery), The Sixth Affiliated Hospital Sun Yat-sen University Guangzhou China.
Rongqin ZhangBiomedical Innovation Center, The Sixth Affiliated Hospital Sun Yat-sen University Guangzhou China.
Taixuan WanDepartment of General Surgery (Colorectal Surgery), The Sixth Affiliated Hospital Sun Yat-sen University Guangzhou China.
Xiaolin PangGuangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital Sun Yat-sen University Guangzhou China.
Zhanwen ZhangBiomedical Innovation Center, The Sixth Affiliated Hospital Sun Yat-sen University Guangzhou China.
Liang HuangDepartment of General Surgery (Colorectal Surgery), The Sixth Affiliated Hospital Sun Yat-sen University Guangzhou China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Predicting pathological complete response (pCR) after neoadjuvant short-course radiotherapy combined with immunotherapy and chemotherapy remains challenging in microsatellite-stable (MSS) locally advanced rectal cancer. In this prospective exploratory study (ClinicalTrials.gov identifier: NCT06608537), 49 patients received short-course radiotherapy followed by sintilimab plus CAPOX and subsequently underwent radical surgery. We investigated whether treatment response could be better characterized by integrating two complementary biological dimensions: baseline immune organization and treatment-related stromal remodeling captured by multi-time-point

Indexed as

cancer‐associated fibroblastsFAPI PET/CTmulti‐time‐point imagingpathological complete responserectal cancertertiary lymphoid structures

Identifiers

PMID42872124
PMCPMC13660711

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.