Evidence map›Paper›PMID 42872113›Full record

ArticleOpen forum infectious diseases2026

Cytomegalovirus Viremia Is Strongly Associated With 6-Month Mortality Among Adults Living With Advanced HIV Disease: A Prospective Cohort Study in South Africa.

Jayne Ellis, Nelesh P Govender, Nei-Yuan Hsiao, Tanvier Omar, Carolina Nel, Ahmad Haeri Mazanderani, Caroline T Tiemessen, Thomas S Harrison, Joseph N Jarvis, Rachel M Wake

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In one paragraph

Article in Open forum infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jayne EllisDepartment of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK.ORCID https://orcid.org/0000-0002-7009-9144
Nelesh P GovenderWits Mycology Division, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.ORCID https://orcid.org/0000-0001-7869-9462
Nei-Yuan HsiaoDepartment of Pathology, University of Cape Town, Cape Town, South Africa.ORCID https://orcid.org/0000-0003-4926-6216
Tanvier OmarDepartment of Anatomical Pathology, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Carolina NelWits Mycology Division, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Ahmad Haeri MazanderaniCentre for HIV and STIs, National Institute for Communicable Diseases, A Division of the National Health Laboratory Service, Johannesburg, South Africa.ORCID https://orcid.org/0000-0001-7644-153X
Caroline T TiemessenCentre for HIV and STIs, National Institute for Communicable Diseases, A Division of the National Health Laboratory Service, Johannesburg, South Africa.
Thomas S HarrisonInstitute for Infection and Immunity, City St George's University of London, London, UK.ORCID https://orcid.org/0000-0003-3619-4348
Joseph N JarvisDepartment of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK.ORCID https://orcid.org/0000-0003-1459-5554
Rachel M WakeWits Mycology Division, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Funding

Wellcome Trust
6 · The paper itself

Abstract

Cytomegalovirus viremia was detected in 59% (86/146) of adults with very advanced human immunodeficiency virus (HIV) disease (CD4 < 100 cells/µL) attending care in South Africa and was strongly associated with increased 6-month mortality after adjustment for CD4 count and antiretroviral therapy (adjusted odds ratio 4.02, 95% CI 1.27-12.7).

Indexed as

AIDScytomegalovirusHIVminimally invasive autopsy

Identifiers

PMID42872113
PMCPMC13660684

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.