Evidence map›Paper›PMID 42872093›Full record

ArticleACS pharmacology & translational science2026

Translational Pharmacokinetic and Pharmacodynamic Evaluation of Mefloquine Against

Sabiha R Mim, Kiana Pica, Lili Liu, Yanan Zang, Yinzhi Lang, Jürgen B Bulitta, Francine Johansson Azeredo

Abstract read
In one paragraph

Article in ACS pharmacology & translational science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sabiha R MimCenter for Pharmacometrics and Systems Pharmacology, Department of Pharmaceutics, College of Pharmacy, University of Florida, Orlando Florida 32827, United States.
Kiana PicaCenter for Pharmacometrics and Systems Pharmacology, Department of Pharmaceutics, College of Pharmacy, University of Florida, Orlando Florida 32827, United States.
Lili LiuDepartment of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis Tennessee 38105, United States.
Yanan ZangDepartment of Pharmaceutics, University of Florida, College of Pharmacy, Center Drive, Gainesville Florida 32610, United States.
Yinzhi LangDepartment of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis Tennessee 38105, United States.
Jürgen B BulittaDepartment of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis Tennessee 38105, United States.ORCID https://orcid.org/0000-0001-7352-3097
Francine Johansson AzeredoCenter for Pharmacometrics and Systems Pharmacology, Department of Pharmaceutics, College of Pharmacy, University of Florida, Orlando Florida 32827, United States.ORCID https://orcid.org/0000-0003-3625-0186

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study established a plastic-based hollow fiber infection model (HFIM) to reproduce human-like mefloquine exposure and quantify antimalarial pharmacodynamics (PD) against blood-stage

Indexed as

hollow fiber infection model (HFIM)mefloquinepharmacokinetic-pharmacodynamic modeling

Identifiers

PMID42872093
PMCPMC13659849

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.