osa-miR166g-3p Mimic Reduces Hepatic Triglyceride Accumulation in Mice.

Yun Lin, Motofumi Kumazoe, Ryouya Watanabe, Chihiro Inoue, Yu Shimada, Yoshinori Fujimura, Hirofumi Tachibana

Abstract read

In one paragraph

Article in ACS pharmacology & translational science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yun LinDivision of Applied Biological Chemistry, Department of Bioscience and Biotechnology, Faculty of Agriculture, Kyushu University, Fukuoka 819-0395, Japan.

Motofumi KumazoeDivision of Applied Biological Chemistry, Department of Bioscience and Biotechnology, Faculty of Agriculture, Kyushu University, Fukuoka 819-0395, Japan.

Ryouya WatanabeDivision of Applied Biological Chemistry, Department of Bioscience and Biotechnology, Faculty of Agriculture, Kyushu University, Fukuoka 819-0395, Japan.

Chihiro InoueDivision of Applied Biological Chemistry, Department of Bioscience and Biotechnology, Faculty of Agriculture, Kyushu University, Fukuoka 819-0395, Japan.

Yu ShimadaDivision of Applied Biological Chemistry, Department of Bioscience and Biotechnology, Faculty of Agriculture, Kyushu University, Fukuoka 819-0395, Japan.

Yoshinori FujimuraDivision of Applied Biological Chemistry, Department of Bioscience and Biotechnology, Faculty of Agriculture, Kyushu University, Fukuoka 819-0395, Japan.ORCID https://orcid.org/0000-0003-0798-0649

Hirofumi TachibanaDivision of Applied Biological Chemistry, Department of Bioscience and Biotechnology, Faculty of Agriculture, Kyushu University, Fukuoka 819-0395, Japan.ORCID https://orcid.org/0000-0003-4820-2122

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatic triglyceride accumulation reflects an imbalance in hepatic lipid metabolism, and pharmacological approaches that enhance fatty acid utilization may provide a strategy for reducing excessive lipid accumulation in the liver. Here, we evaluated the effects of a synthetic osa-miR166g-3p mimic, corresponding to a microRNA sequence originally identified in

Indexed as

AMPKfatty acid β-oxidationhepatic lipid accumulationosa-miR166g-3pplant miRNA mimicPPARα

Identifiers

PMID42872012

DOI10.1021/acsptsci.6c00406

PMCPMC13659850

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.