ArticleFood science & nutrition2026
Maternal Diglyceride Diet Attenuates Selected Metabolic Effects of Maternal High-Fat Feeding in Offspring via Energy Metabolism and Microbiota Modulation.
Article in Food science & nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Diglyceride (DAG) has been shown to improve obesity in animals, but its effects on mothers and offspring were unclear. This study investigated whether maternal DAG intake affects male offspring by mating female C57BL/6J mice on a DAG diet with normal males. Male offspring were weaned at 3 weeks, with some euthanized and others fed normal, high-fat (HFD), or DAG diets for 9 weeks. Results showed that offspring from DAG-fed mothers had lower blood lipids than those from HFD-fed mothers, and maternal DAG intake was associated with restoration of purine/pyrimidine metabolism while altering gut microbiota (lower
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