ArticlePrzeglad menopauzalny = Menopause review2026
Modulation of hormones in perimenopausal women by probiotics associated by specific gut bacteria: a pilot study.
Article in Przeglad menopauzalny = Menopause review, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
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Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Perimenopause is characterised by hormonal fluctuations that can affect metabolism. Recent studies suggest that the gut microbiota, which can be regulated by taking probiotics, influences hormone regulation. One proposed mechanism is the activity of β-glucuronidase, which hydrolyzes excreted hormones, allowing them to be reabsorbed. The objective of this study was to investigate the effects of supplementation with Material and methods: A single-arm pre-post pilot study was conducted on 20 perimenopausal women aged 50-55 years who received 10 Results: Probiotic supplementation with Conclusions: It can be concluded that supplementation under the described conditions improves specific bacteria, increases estradiol, and increases β-glucuronidase activity. Although methodological limitations prevent demonstrating a direct impact on quality of life, this mechanistic approach to the estrobolome provides valuable support for guiding the design of new research on hormonal homeostasis in perimenopause.
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