ArticlePhysics and imaging in radiation oncology2026
Feasibility of ultra-low-field MRI in an ion beam treatment room for online MR-guided particle therapy.
Article in Physics and imaging in radiation oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background and purpose: Online MR-guided particle therapy may improve beam delivery precision and treatment efficacy. Ultra-low-field (ULF) MRI may enable image guidance with minimal modification of existing facilities. The feasibility of operating a ULF magnetic resonance (MR) scanner for online MR-guided particle therapy in an unmodified ion-beam therapy environment was investigated. Material and methods: A portable 49 mT ULF-MRI system (OSI Results: Stable image quality was achieved across proton and carbon ion irradiation with no relevant irradiation-induced artifacts. Initially substantial EMI was reduced to near-baseline levels by internal shielding. Proton beam deflections ranged from 0.9-1.7 mm at isocenter, consistent with simulations. Dosimetric deviations were below 0.05% for 2D fields and 0.02% for spread-out Bragg peaks (SOBP). Conclusion: ULF-MRI operation in an ion-beam therapy environment without a dedicated shielded room is feasible, without compromising imaging, beam delivery, or dosimetry. This approach supports future MR-guided particle therapy research with reduced infrastructural requirements.
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