Evidence map›Paper›PMID 42871731›Full record

ArticleExercise, sport & movement2027

Changes in Hormone Cycles and Exercise Capacity During Testosterone Therapy in a Transmasculine Triathlete: A Case Study.

Skyler R St Pierre, Sarah C Johnson, Julie Muccini, Brianna Bourne, Benjamin H Laniakea, Scott L Delp, Jennifer L Hicks

Abstract read
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Article in Exercise, sport & movement, 2027. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Skyler R St PierreDepartment of Mechanical Engineering, Stanford University, Stanford, CA, USA.
Sarah C JohnsonDepartment of Bioengineering, Stanford University, Stanford, CA, USA.
Julie MucciniDepartment of Radiology, Stanford University, Stanford, CA, USA.
Brianna BourneDepartment of Cardiovascular Medicine, Stanford University, Stanford, CA, USA.
Benjamin H LaniakeaDepartment of Medicine, Stanford University, Stanford, CA, USA.
Scott L DelpDepartment of Mechanical Engineering, Stanford University, Stanford, CA, USA.
Jennifer L HicksDepartment of Bioengineering, Stanford University, Stanford, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The impact of testosterone therapy on the hormone cycles, exercise capacity, and physiology of transmasculine individuals is not well understood. Existing studies report limited metrics at large time intervals between data collection points. Methods: High-resolution temporal data were collected from a single amateur trans male triathlete over 13 months-including one baseline month and 12 months on testosterone therapy-to characterize hormone, strength, body composition, aerobic, and training load profiles. Results: Daily urine hormone monitoring revealed that progesterone and luteinizing hormone are the clearest metrics associated with cessation of menses. After 1 yr, the participant increased lean body mass by 12%, average hand grip strength by 16%, jump height by 16%, and average knee isometric strength by 18%, but did not lose fat mass or show changes in isokinetic knee strength. Fluctuations in running fitness and maximum oxygen consumption ( Conclusion: This study provides the most comprehensive characterization of the impacts of testosterone therapy on hormone cycles, exercise capacity, and physiological changes in a single person to date, as well as observations to help inform the design of larger cohort studies.

Indexed as

amateur athleteexercisegender-affirming hormone therapyphysiologytestosteronetrans

Identifiers

PMID42871731
PMCPMC13660064

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.