Evidence map›Paper›PMID 42871667›Full record

ArticleSleep advances : a journal of the Sleep Research Society2026

Napping during major depressive episodes identifies a distinct hypersomnolence phenotype.

Pierre Alexis Geoffroy, Célia Heiligenstein, Sibylle Mauries, Justin Ulm, Fériel Zehani, Chantal Henry, Michel Lejoyeux, Patrice Bourgin, Julia Maruani

Abstract read
In one paragraph

Article in Sleep advances : a journal of the Sleep Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Pierre Alexis GeoffroyDépartement de psychiatrie et d'addictologie, AP-HP, GHU Paris Nord, DMU Neurosciences, Hôpital Bichat-Claude Bernard, Paris F-75018, France.ORCID https://orcid.org/0000-0001-9121-209X
Célia HeiligensteinHôpitaux Universitaires de Strasbourg, Service de Pédopsychiatrie de l'Enfant et de l'Adolescent Strasbourg.
Sibylle MauriesDépartement de psychiatrie et d'addictologie, AP-HP, GHU Paris Nord, DMU Neurosciences, Hôpital Bichat-Claude Bernard, Paris F-75018, France.
Justin UlmEmergency Department, Percy military teaching hospital, Clamart 92140, France.
Fériel ZehaniDépartement de psychiatrie et d'addictologie, AP-HP, GHU Paris Nord, DMU Neurosciences, Hôpital Bichat-Claude Bernard, Paris F-75018, France.
Chantal HenryUniversité Paris Cité, NeuroDiderot, Inserm, Paris F-75019, France.
Michel LejoyeuxDépartement de psychiatrie et d'addictologie, AP-HP, GHU Paris Nord, DMU Neurosciences, Hôpital Bichat-Claude Bernard, Paris F-75018, France.
Patrice BourginCNRS UPR 3212, Institute for Cellular and Integrative Neurosciences, Strasbourg University, F-67000, France.
Julia MaruaniDépartement de psychiatrie et d'addictologie, AP-HP, GHU Paris Nord, DMU Neurosciences, Hôpital Bichat-Claude Bernard, Paris F-75018, France.ORCID https://orcid.org/0000-0002-2002-6051

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Study Objectives: Prior studies have linked depression with napping, though findings remain inconsistent. Given that major depressive episodes (MDE) commonly involve sleep-wake and circadian disturbances, we hypothesized that daytime Napping during MDE reflects more pronounced sleep/circadian disruptions and a distinct clinical profile. Materials and Methods: We compared MDE patients with and without napping (MDE-NAP vs MDE), as well as unipolar and bipolar subgroups, using subjective and objective biomarkers, including actigraphy. Results: The MDE-NAP group had more frequently hypersomnia (30.6% vs 8.2% Conclusions: Daytime napping during MDE appears to identify a distinct hypersomnolence phenotype with sleep-vegetative burden, supporting the systematic assessment of napping to guide personalized sleep- and circadian-based therapeutic strategies.

Indexed as

biological clockbipolar disordersdepressionexcessive daytime sleepinessnapsleep–wake disorderunipolar disorders

Identifiers

PMID42871667
PMCPMC13660474

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.