ArticlePregnancy (Hoboken, N.J.)2026
Social determinants of health associated with newly documented opioid-related postpartum readmissions.
Article in Pregnancy (Hoboken, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Peripartum opioid-related mortality has increased in recent years, and social determinants of health (SDOH) are associated with adverse maternal outcomes. We sought to identify risk factors (including SDOH risk factors) for 180-day postpartum readmissions related to opioid use among individuals without a documented diagnosis of opioid use at delivery. Methods: We performed a retrospective cohort study using 2016-2021 data from the Nationwide Readmissions Database. Delivery hospitalizations and subsequent 180-day postpartum readmissions with a new opioid-use diagnosis were identified. Newly documented opioid use was defined as opioid dependence, abuse, or overdose documented at readmission without evidence of opioid use disorder at or prior to delivery. SDOH exposures were categorized into domains reflecting education/employment, physical environment, and social factors using International Classification of Diseases (ICD)-10 codes. Temporal trends in opioid use-related postpartum readmissions were evaluated using joinpoint regression to estimate average annual percent change (AAPC) with 95% confidence intervals (CIs). Multivariable logistic regression was used to estimate associations between SDOH and 180-day newly documented opioid use readmission, adjusting for demographic and clinical factors. Results: Among 10,278,674 delivery hospitalizations, 3129 individuals (3.0 per 10,000) experienced a postpartum readmission with newly documented opioid use. The rate of 180-day postpartum opioid-related readmission declined from 3.7 to 2.2 per 10,000 delivery hospitalizations between 2016 and 2021 (AAPC, -10.4%; 95% CI, -13.5% to -7.8%). In unadjusted models, education- or employment-related SDOH (odds ratio [OR], 6.26; 95% CI, 2.70-14.51), SDOH related to the physical environment, housing, or economic circumstances (OR, 20.93; 95% CI, 14.81-29.57), and social SDOH (OR, 4.09; 95% CI, 2.51-6.65) were associated with opioid-related readmission. In adjusted models, only SDOH related to the physical environment, housing, or economic circumstances remained independently associated with opioid-related readmission (adjusted odds ratio [aOR], 4.87; 95% CI, 3.35-7.09). Conclusion: Although postpartum readmissions for newly documented opioid use have declined nationally, individuals experiencing adverse physical environment-related SDOH remain at significantly elevated risk. Early identification of structural vulnerability and linkage to supportive services may help reduce opioid-related postpartum morbidity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.