Evidence map›Paper›PMID 42871328›Full record

ArticleFrontiers in digital health2026

Real-world deployment and longitudinal evaluation of a human-in-the-loop telemedicine communication support system.

Roland Roller, Ajay Madhavan Ravichandran, Tillmann-Leonhard Breitenstein, Marcel Naik, Bianca Zukunft, Bilgin Osmanodja, Matthias Pfefferkorn, Tim Gielsdorf, Judith Schleder, Sinem Karaterzi and 13 more

Abstract read
In one paragraph

Article in Frontiers in digital health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Roland RollerSpeech and Language Technology Lab, German Research Center for Artificial Intelligence (DFKI), Berlin, Germany.
Ajay Madhavan RavichandranSpeech and Language Technology Lab, German Research Center for Artificial Intelligence (DFKI), Berlin, Germany.
Tillmann-Leonhard BreitensteinDepartment of Nephrology and Medical Intensive Care, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Marcel NaikDepartment of Nephrology and Medical Intensive Care, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Bianca ZukunftDepartment of Nephrology and Medical Intensive Care, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Bilgin OsmanodjaDepartment of Nephrology and Medical Intensive Care, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Matthias PfefferkornDepartment of Nephrology and Medical Intensive Care, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Tim GielsdorfDepartment of Nephrology and Medical Intensive Care, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Judith SchlederDepartment of Nephrology and Medical Intensive Care, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Sinem KaraterziDepartment of Infectious Diseases and Nephrology, University Hospital Essen, Essen, Germany.
Kristina BossDepartment of Infectious Diseases and Nephrology, University Hospital Essen, Essen, Germany.
Philipp WinnekensDepartment of Infectious Diseases and Nephrology, University Hospital Essen, Essen, Germany.
Mario A CypkoHahn-Schickard-Gesellschaft für angewandte Forschung e.V., Freiburg, Germany.
Aditya KumarHahn-Schickard-Gesellschaft für angewandte Forschung e.V., Freiburg, Germany.
Ulrich KunzeDepartment of Medicine 4 - Nephrology and Hypertension, University Hospital Erlangen, Erlangen, Germany.
Lisa RaithelSpeech and Language Technology Lab, German Research Center for Artificial Intelligence (DFKI), Berlin, Germany.
Oliver WitzkeDepartment of Infectious Diseases and Nephrology, University Hospital Essen, Essen, Germany.
Oliver AmftHahn-Schickard-Gesellschaft für angewandte Forschung e.V., Freiburg, Germany.
Lars PapeDepartment of Infectious Diseases and Nephrology, University Hospital Essen, Essen, Germany.
Sebastian MöllerSpeech and Language Technology Lab, German Research Center for Artificial Intelligence (DFKI), Berlin, Germany.
Mario SchifferDepartment of Medicine 4 - Nephrology and Hypertension, University Hospital Erlangen, Erlangen, Germany.
Klemens BuddeDepartment of Nephrology and Medical Intensive Care, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Wiebke DuettmannVivantes, Auguste Viktoria Krankenhaus, Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Telemedicine platforms are increasingly used to support the long-term monitoring of chronically ill patients. However, continuous streams of patient-reported data and messages may impose substantial workload on telemedicine teams. To address this challenge, we developed a human-in-the-loop communication support system for telemedicine monitoring of kidney transplant recipients. Methods: The system was integrated into the telemedicine program of the nephrology department at Charité - Universitätsmedizin Berlin. It analyzes telemedicine data in combination with locally stored electronic health record (EHR) data and generates suggested responses and reminders for clinical staff. All suggestions are reviewed by telemedicine personnel and can be accepted, modified, or discarded before being sent to patients. System usage was evaluated based on routine operation data collected since deployment. Results: The system has been in productive use since May 15, 2024. During the observation period, more than 22,000 message suggestions were generated, of which over 16,000 were sent without modification. Overall, approximately 76% of all generated suggestions resulted in patient communication. Usage increased steadily over time, indicating successful integration into routine telemedicine workflows. Standardized reminders and routine communication tasks showed particularly high utilization. Conclusions: Our findings demonstrate the potential of automated communication support systems to assist routine telemedicine workflows while maintaining human oversight of patient communication. At the same time, practical challenges related to system integration, data timeliness, and context awareness remain important considerations for successful deployment in clinical environments.

Indexed as

adherencechat-supporthuman-in-the-loopnephrologytelemedicine

Identifiers

PMID42871328
PMCPMC13658540

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.