ArticleJournal of clinical practice and research2026
Clinical Relevance of Multiplex PCR for Respiratory Pathogens in Hospitalized Adults with Influenza-Like Illness.
Article in Journal of clinical practice and research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: Influenza-like illness (ILI) is a major cause of hospitalization during respiratory virus seasons. This study aimed to investigate the pathogens detected in patients presenting with ILI symptoms and to analyze the results in conjunction with clinical, laboratory, and radiological findings. Materials and Methods: This retrospective, single-center study included 446 hospitalized adults with ILI between epidemiological week 40 of 2024 and week 20 of 2025. Respiratory pathogens were identified using a multiplex real-time polymerase chain reaction (PCR) assay detecting 18 viral and 5 bacterial pathogens. Demographic, clinical, laboratory, and radiological data were retrieved from electronic medical records. Disease severity was assessed using the CURB-65 score. Patients with Results: At least one respiratory pathogen was detected in 184/446 patients (41.2%), whereas no pathogen was identified in 262 patients (58.8%). The most frequently detected pathogens were Conclusion: Multiplex molecular assays provide valuable information for respiratory pathogen detection, but molecular results, especially for bacterial pathogens such as
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