ArticleFrontiers in medicine2026
Quantitative CT-derived small pulmonary vessel and erector spinae muscle parameters associated with acute exacerbation in COPD patients from a cold region: a dual-center study.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: To investigate the association of quantitative CT-derived erector spinae muscle and small pulmonary vessel parameters with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) in a cold-region population and construct a combined model to evaluate their joint discriminative value. Methods: This retrospective dual-center study included 273 patients with COPD from two centers in a cold region of northern China and divided them into non-AECOPD and AECOPD groups. Clinical characteristics, pulmonary function, and quantitative CT parameters, including erector spinae muscle cross-sectional area (CSA), volume, muscle attenuation, CSA/BMI, CSA × CT, and the percentage of small pulmonary vessel area <5 mm Results: Compared with the non-AECOPD group, the AECOPD group had significantly lower CSA, volume, muscle attenuation, CSA/BMI, CSA × CT, and %Vessel < 5 (all Conclusion: Quantitative CT-derived CSA/BMI and %Vessel < 5 are independently associated with AECOPD and may provide complementary imaging information for characterizing patients with COPD.
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