ArticleFrontiers in cardiovascular medicine2026
Comparative midterm outcomes of contemporary revascularization strategies for acute lower limb ischemia: a retrospective cohort study.
Article in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Acute lower limb ischaemia (ALLI) is a vascular emergency associated with high morbidity and mortality. Contemporary revascularization strategies include open surgery,endovascular intervention,and hybrid approaches,yet comparative midterm outcomes remain incompletely defined. Methods: We conducted a single - center retrospective cohort study of 842 consecutive patients with ALLI treated at Xinxiang City Central Hospital between January 2019 and December 2023,with follow - up complete through May 2026.Patients underwent open surgery( Results: The mean age was 74 ± 13, 70 ± 12,and 71 ± 13 years in the open, endovascular, and hybrid groups, respectively. Endovascular treatment was associated with lower peri - operative mortality (adjusted OR 0.32,95% CI 0.15-0.68, Conclusions: Endovascular revascularization for ALLI offers improved peri - operative safety and favorable midterm composite outcomes compared with open surgery in this observational cohort. Hybrid strategies demonstrate intermediate results. These findings support individualized treatment selection, but definitive causal inferences are limited by the non - randomized design and potential residual confounding.
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