ArticleMicrobiologyOpen2026
Modulation of Early-Life Calf Gut Microbiota by Bacteriocin-Producing Lactiplantibacillus pentosus AA86 and Pediococcus pentosaceus AA94.
Article in MicrobiologyOpen, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 authors.
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Abstract
Early-life gut microbiota plays a critical role in livestock health and productivity. Probiotic interventions, particularly those employing bacteriocin-producing lactic acid bacteria (LAB), may contribute to modulation of microbial development during this critical period. This study evaluated Lactiplantibacillus pentosus AA86 (formerly Lactobacillus pentosus) and Pediococcus pentosaceus AA94 for genomic safety, bacteriocin potential, and their effects on calf gut microbiota. Whole-genome sequencing assessed antimicrobial resistance genes, virulence determinants, plasmid-associated elements, and bacteriocin-encoding genes. Both strains lacked detectable antimicrobial resistance genes, virulence determinants, and plasmid-related elements, while harboring pediocin-encoding genes consistent with potential antimicrobial functionality. In a 30-day feeding trial, eight calves (50 ± 10 kg) were assigned to a control group (sterile skimmed milk, n = 2) or a probiotic group (milk supplemented with both strains at ~8.6 × 10
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