Evidence map›Paper›PMID 42870638›Full record

ArticleChemistry & biodiversity2026

Bioactive Compounds and Antidiabetic Properties of Launaea mucronata Hydroethanolic Extract: Phytochemical and Pharmacological Insights.

Amira Mohamed, Dalia El Amir, Maha M Abdel-Fattah, Mohamed A Zaki, Rabab Mohammed, Marwa H A Hassan

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Article in Chemistry & biodiversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Amira MohamedDepartment of Pharmacognosy, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.ORCID https://orcid.org/0000-0002-0442-7234
Dalia El AmirDepartment of Pharmacognosy, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.ORCID https://orcid.org/0000-0002-2390-6337
Maha M Abdel-FattahDepartment of Pharmacology and Toxicology, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.ORCID https://orcid.org/0000-0002-9019-8932
Mohamed A ZakiDepartment of Pharmacognosy, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.ORCID https://orcid.org/0000-0003-4889-8836
Rabab MohammedDepartment of Pharmacognosy, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.ORCID https://orcid.org/0000-0001-9683-4250
Marwa H A HassanDepartment of Pharmacognosy, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.ORCID https://orcid.org/0000-0002-0952-5984

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Launaea mucronata has been traditionally used in folk medicine worldwide for managing various diseases. This study investigated the phytochemical composition and biological activities of the hydroethanolic extract of L. mucronata aerial parts. Total phenolic and flavonoid contents were 63.77 ± 0.21 mg GAE/g and 20.91 ± 1.56 mg QE/g, respectively. Phytochemical investigation yielded lupeol (1) and β-sitosterol (2) from the n-hexane fraction; ethyl caffeate (3) and apigenin (4) from the dichloromethane fraction; apigenin (4), luteolin (5), and apigenin-7-O-glucuronide (6) from the ethyl acetate fraction. Antioxidant capacity, assessed via 2,2‑diphenyl‑1‑picrylhydrazyl (DPPH, 109.30 ± 0.75 mg AAE/g) and phosphomolybdenum (119.18 ± 0.93 mg AAE/g) assays, was notable. The extract also showed significant antidiabetic potential, inhibiting α-glucosidase (IC

Indexed as

Diabetes Mellitus, ExperimentalHypoglycemic AgentsPhytochemicalsPlant ExtractsSolanaceaealpha-Amylasesalpha-GlucosidasesAnimalsAntioxidantsBiphenyl CompoundsEthanolFlavonoidsGlycoside Hydrolase InhibitorsMalePicratesPlant Components, Aerial1,1-diphenyl-2-picrylhydrazylalpha-Amylasesalpha-GlucosidasesAntioxidantsBiphenyl CompoundsEthanolFlavonoidsGlycoside Hydrolase InhibitorsHypoglycemic AgentsPhytochemicalsPicratesPlant ExtractsantidiabeticantioxidantLaunaea mucronataα‐amylaseα‐glucosidase

Identifiers

PMID42870638
PMCPMC13662495

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.