ArticleBone & joint research2026
Differences in the collagen of semitendinosus tendon in patients with and without general joint laxity.
Article in Bone & joint research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aims: Generalized joint laxity (GJL) has been reported to be a risk factor for anterior cruciate ligament (ACL) graft injury. There are no reports of differences in the collagen content of semitendinosus tendons used as graft tendon being a risk factor for ACL graft injury. The aim of this study was to determine the differences in the collagen type content in the semitendinosus tendon in patients with and without GJL. Methods: In total, 36 knees from 36 patients who underwent ACL reconstruction were analyzed. GJL was assessed using the Beighton score, with GJL defined as a Beighton score of ≥ 4, ≥ 5, or ≥ 6. The patients were divided into two groups: those with GJL (G-group) and those without (N-group). The parameters included the quantification of collagen types I, III, V, and XII in semitendinosus tendons via immunohistochemical staining, alongside preoperative radiological evaluation of the knee joint laxity. Comparisons were made between the two groups, and the correlation between the Beighton score and collagen content was analyzed. Results: There were significant differences between the G-group and the N-group in the type III collagen content (117.9 (SD 17.4) vs 130.0 (SD 11.5), p = 0.036) and the joint line convergence angle (JLCA) under varus stress (6.3° (SD 1.9°) vs 4.6° (SD 2.0°), p = 0.021) only when a Beighton score of ≥ 6 was defined as GJL. Hyperextension of the knee under anaesthesia differed significantly between the two groups across all definitions of GJL. The Beighton score was significantly correlated with the type III collagen content ( Conclusion: Patients with GJL exhibited significantly higher collagen type III content in the semitendinosus tendon compared to those without GJL.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.