Evidence map›Paper›PMID 42868085›Full record

ArticleBJS open2026

Smoking, obesity and reoperation after elective open mesh repair of umbilical hernia: nationwide cohort study.

Jeppe Fredberg, Erling Oma, Frederik Helgstrand, Lars N Jorgensen

Abstract read
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Article in BJS open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Jeppe FredbergDigestive Disease Centre, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.ORCID 0009-0008-9709-9647
Erling OmaDigestive Disease Centre, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0003-0273-8992
Frederik HelgstrandDepartment of Surgery, Zealand University Hospital, Koege, Denmark.ORCID 0000-0001-5702-8352
Lars N JorgensenDigestive Disease Centre, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0001-7465-5374

Funding

Bispebjerg HospitalEdgar Schnohrs og Hustru's FundProsektor Dr. med. Axel Emil Søeborg Ohlsen og Ægtefælde Else Søeborg Ohlsens Mindelegat
6 · The paper itself

Abstract

introductionEvidence of the effects of obesity and smoking on complication-related reintervention after elective umbilical hernia mesh repair is limited. This study evaluated the association between these factors and reoperation after mesh repair.

methodsA nationwide cohort of elective open umbilical hernia repairs from 2017 to 2020 was identified from prospective registration in the Danish Hernia Database. Patients were followed until 31 December 2023 through nationwide registries and complete scrutiny of operative notes associated with succeeding reinterventions. Study outcomes were reoperation for any complication, recurrence, or non-recurrence complication with special reference to the repair method. Multivariable analyses included cause-specific hazard models with adjustment for body mass index (BMI), smoking status, sex, age, and hernia size.

resultsOf the 2391 patients included in the study, 18.4% were smokers and 34.0% were obese (BMI > 30 kg/m2). The follow-up rate was 99.9% over a median of 4.65 years. Reoperation for any complication was increased in smokers compared with non-smokers (hazard ratio (HR) 1.68; 95% confidence interval (c.i.) 1.05 to 2.69; P = 0.032). Reoperation for non-recurrence complications was more frequent in smokers (HR 2.01; 95% c.i. 1.19 to 3.38; P = 0.009) and obese patients (HR 1.83; 95% c.i. 1.12 to 3.00; P = 0.016). Comparable risks of reoperation for hernia recurrence were found between smokers and non-smokers (HR 0.80; 95% c.i. 0.23 to 2.73; P = 0.721) and between patients with and without obesity (HR 0.73; 95% c.i. 0.26 to 2.09; P = 0.559).

conclusionReoperation for any complication after open umbilical hernia mesh repair was more frequent in smokers, whereas no independent association was observed between patients with and without obesity. Smoking and obesity were associated with an increased risk of reoperation for non-recurrence complications, while not affecting reoperation for hernia recurrence.

Indexed as

Elective Surgical ProceduresHernia, UmbilicalHerniorrhaphyObesityPostoperative ComplicationsReoperationSmokingAdultAgedBody Mass IndexCohort StudiesDenmarkFemaleHumansMaleMiddle Agedbody mass indexelective surgeryhernia repairpostoperative complicationstobacco

Identifiers

PMID42868085
PMCPMC13660690

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.