Evidence map›Paper›PMID 42867880›Full record

ReviewMicrobiology (Reading, England)2026

How cystic fibrosis modulator therapy could transform

James Gurney, Morgana Letizia, Sheyda Azimi, Stephen P Diggle

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Microbiology (Reading, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

James GurneySchool of Biology, Georgia State University, Atlanta, Georgia, USA.
Morgana LetiziaCenter for Microbial Dynamics & Infection, School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA.
Sheyda AzimiSchool of Biology, Georgia State University, Atlanta, Georgia, USA.
Stephen P DiggleCenter for Microbial Dynamics & Infection, School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA.

Funding

Understanding in vivo antibiotic resistance in diverse Pseudomonas aeruginosa populationsR01AI153116 · NIAID · GEORGIA INSTITUTE OF TECHNOLOGY · PI DIGGLE, STEPHEN PAUL · 2021 to 2025
$2.3M
Deciphering How Bacterial Surface Properties Influence Social BehaviorsR56AI184449 · NIAID · GEORGIA INSTITUTE OF TECHNOLOGY · PI DIGGLE, STEPHEN PAUL · 2024 to 2024
$454k
NIAID NIH HHS R01 AI153116NIAID NIH HHS R56 AI184449
6 · The paper itself

Abstract

The advent of cystic fibrosis transmembrane conductance regulator modulators has revolutionized cystic fibrosis (CF) care by restoring epithelial ion transport and improving airway physiology in people with CF. These therapies reduce infection burden, especially from

Indexed as

Cystic FibrosisCystic Fibrosis Transmembrane Conductance RegulatorPseudomonas aeruginosaPseudomonas InfectionsBiofilmsHumansVirulenceCystic Fibrosis Transmembrane Conductance RegulatorCFTR modulatorschronic infectioncystic fibrosismicrobial adaptationpathogen evolutionPseudomonas aeruginosa

Identifiers

PMID42867880
PMCPMC13661130

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.