Evidence map›Paper›PMID 42867635›Full record

ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2026

Sex-specific predictive equations for estimating trochanteric soft tissue thickness across body positions and imaging modalities.

Alyssa M Tondat, Benoit R Lafleur, Marina Mourtzakis, Andrew C Laing

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Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

4 authors.

Alyssa M TondatDepartment of Kinesiology and Health Sciences, University of Waterloo, Waterloo, ON, Canada.
Benoit R LafleurDepartment of Kinesiology and Health Sciences, University of Waterloo, Waterloo, ON, Canada.
Marina MourtzakisDepartment of Kinesiology and Health Sciences, University of Waterloo, Waterloo, ON, Canada.
Andrew C LaingDepartment of Kinesiology and Health Sciences, University of Waterloo, Waterloo, ON, Canada. actlaing@uwaterloo.ca.ORCID http://orcid.org/0000-0001-8128-011X

Funding

Natural Sciences and Engineering Research Council of Canada RGPIN-2015-03636Ontario Ministry of Research and Innovation ER14-10-236
6 · The paper itself

Abstract

Soft tissue thickness is an important factor in fall-related hip fractures. However, methods used to measure soft tissue thickness are inconsistent. We developed sex-specific equations for estimating soft tissue thickness between body positions and imaging modalities. The equations support across-study comparisons and refinement of sex-specific hip fracture risk prediction tools.

introductionTrochanteric soft tissue thickness (TSTT), which is the amount of soft tissues overlying the greater trochanter, may improve hip fracture risk assessments by improving estimates of the impact force applied to the hip during a fall. Accordingly, TSTT is an important variable to consider in hip fracture risk assessment. However, measurement of TSTT is inconsistent, with different body positions (supine, side-lying, standing) and imaging modalities (ultrasound, dual-energy X-ray absorptiometry (DXA)) being used. PURPOSE: The objectives of this study were to develop sex-specific regression equations to allow for estimation of 1) ultrasound-measured TSTT across three common body positions, and 2) ultrasound-based TSTT from DXA-derived TSTT.

methodsMeasurements of TSTT were obtained in standing, supine, and side-lying positions using ultrasound, and from a whole-body DXA scan in 45 community-dwelling older adults. Sex-specific linear regression equations were developed for estimating ultrasound-measured TSTT across body positions, and for estimating ultrasound-measured TSTT from DXA-derived TSTT.

resultsLinear regression models revealed significant positive relationships between ultrasound-measured TSTT across all body positions and by DXA and ultrasound-measured TSTT in all body positions (r

conclusionsThe regression equations from this study can be used to estimate TSTT between body positions and imaging modalities. The data provide valuable tools to support across-study comparisons and further refinement of sex-specific hip fracture risk prediction tools.

Indexed as

Dual energy X-ray absorptiometryHip fractureTSTTUltrasound

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.