Evidence map›Paper›PMID 42867181›Full record

ArticleSICOT-J2026

Unexpected positive intraoperative culture during supposed aseptic hip revision: Antibiotherapy is an effective and safe treatment. About 50 cases.

Guillaume Auberger, Pierre-Alban Bouché, Thomas Aubert, Luc Lhotellier, Younes Kerroumi, Beate Heym, Valérie Zeller, Simon Marmor

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Article in SICOT-J, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Guillaume AubergerDepartment of Orthopedic and Trauma Surgery, Diaconesses Croix St-Simon Hospital Group, 125 rue d'Avron, 75020 Paris, France - Reference Center for Complex Osteoarticular Infection (CRIOA), Diaconesses Croix St-Simon Hospital Group, 125 rue d'Avron, 75020 Paris, France.ORCID 0000-0002-2314-4133
Pierre-Alban BouchéDepartment of Orthopedic and Trauma Surgery, Diaconesses Croix St-Simon Hospital Group, 125 rue d'Avron, 75020 Paris, France - Reference Center for Complex Osteoarticular Infection (CRIOA), Diaconesses Croix St-Simon Hospital Group, 125 rue d'Avron, 75020 Paris, France.
Thomas AubertDepartment of Orthopedic and Trauma Surgery, Diaconesses Croix St-Simon Hospital Group, 125 rue d'Avron, 75020 Paris, France - Reference Center for Complex Osteoarticular Infection (CRIOA), Diaconesses Croix St-Simon Hospital Group, 125 rue d'Avron, 75020 Paris, France.
Luc LhotellierDepartment of Orthopedic and Trauma Surgery, Diaconesses Croix St-Simon Hospital Group, 125 rue d'Avron, 75020 Paris, France - Reference Center for Complex Osteoarticular Infection (CRIOA), Diaconesses Croix St-Simon Hospital Group, 125 rue d'Avron, 75020 Paris, France.
Younes KerroumiDepartment of Orthopedic and Trauma Surgery, Diaconesses Croix St-Simon Hospital Group, 125 rue d'Avron, 75020 Paris, France - Reference Center for Complex Osteoarticular Infection (CRIOA), Diaconesses Croix St-Simon Hospital Group, 125 rue d'Avron, 75020 Paris, France.
Beate HeymReference Center for Complex Osteoarticular Infection (CRIOA), Diaconesses Croix St-Simon Hospital Group, 125 rue d'Avron, 75020 Paris, France - Laboratory of Health Centers and Hospitals of Île-de-France, Diaconesses Croix St-Simon Hospital Group, 125 rue d'Avron, 75020 Paris, France.
Valérie ZellerReference Center for Complex Osteoarticular Infection (CRIOA), Diaconesses Croix St-Simon Hospital Group, 125 rue d'Avron, 75020 Paris, France.
Simon MarmorDepartment of Orthopedic and Trauma Surgery, Diaconesses Croix St-Simon Hospital Group, 125 rue d'Avron, 75020 Paris, France - Reference Center for Complex Osteoarticular Infection (CRIOA), Diaconesses Croix St-Simon Hospital Group, 125 rue d'Avron, 75020 Paris, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe management of periprosthetic joint infection (PJI) in revision total hip arthroplasty (rTHA) with unsuspected positive intraoperative cultures (UPC) is not well codified. There are conflicting results in the literature. No study reported the long-term outcomes between single or both component rTHA with UPC. The aim of this study was to compare the overall survival rate of single component revision to total in case of rTHA with UPC using an institutional registry database. The reinfection-free survival rate was assessed as secondary outcomes.

methodsPatients were selected from a PJI institutional registry of THA between March 2003 and May 2020. Fifty rTHA with UPC were finally included in the study: 26 in the both component revision group and 24 in the single component revision group. The mean age of the patients was 64.8 years (range: 30.6; 88.2), 36% (18/50) of the patients were women and with a mean body mass index (BMI) of 27.6 Kg/m2 (range: 19.6; 39.5). Kaplan-Meier analyses were performed to compare overall survival rate between groups.

resultsThe overall survival rate in our series of rTHA with UPC was 70.0% [56.1%-87.2%] at 10 years. Fourteen re-interventions were carried out during the follow-up period (28.0%, 14/50). There was no significant difference between groups (61.4% vs. 79.3% at 10 years, respectively in both and single rTHA, p = 0.76). At the last follow-up, three infections were observed (6%, 3/50): 1 relapse (33.4%) and 2 new infections (66.6%). There was no significant difference between groups (83.2% vs. 100.0% at 10 years, respectively in both and single component rTHA, p = 0.08).

conclusionAntibiotic therapy alone for UPC in a single component revision of a presumed aseptic THA is a safe and effective treatment. Therapeutic study level of evidence, level III retrospective study.

Indexed as

Hip prosthesisProsthesis infectionTsukayamaUnexpected positive cultureUnexpected positive samplings

Identifiers

PMID42867181
PMCPMC13661126

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.