Evidence map›Paper›PMID 42867008›Full record

ArticleCancer reports (Hoboken, N.J.)2026

Peripheral Lymphocyte Subsets Predict Efficacy and Overall Survival in Gastric Cancer Patients Receiving Preoperative Chemotherapy: A Retrospective Cohort Study.

Zirui Xue, Dan Liu, Zhaodong Sun, Bosen Li, Xinyou Liu, Junjie Zhao, Haojie Li, Xuefei Wang, Zhaoming Wang

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PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer reports (Hoboken, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zirui XueDepartment of Gastrointestinal Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.ORCID https://orcid.org/0009-0009-6086-7275
Dan LiuDepartment of Gastrointestinal Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.ORCID https://orcid.org/0000-0002-6376-7597
Zhaodong SunDepartment of Gastrointestinal Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.ORCID https://orcid.org/0009-0007-2737-698X
Bosen LiDepartment of Gastrointestinal Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.ORCID https://orcid.org/0009-0005-7423-3266
Xinyou LiuDepartment of Gastrointestinal Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Junjie ZhaoDepartment of Gastrointestinal Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Haojie LiDepartment of Gastrointestinal Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.ORCID https://orcid.org/0000-0003-0704-8309
Xuefei WangDepartment of Gastrointestinal Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.ORCID https://orcid.org/0009-0004-4014-2094
Zhaoming WangDepartment of Gastrointestinal Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.ORCID https://orcid.org/0000-0001-8308-5297

Funding

National Youth Science Fund Project of National Natural Science Foundation of China 82403871Project of Science and Technology of Xiamen City 3502Z20224015
6 · The paper itself

Abstract

backgroundPathologic complete response (pCR), which reflects the local immune status and preoperative chemotherapy efficacy, has garnered significant attention in gastric cancer research. However, the predictive value of peripheral lymphocyte subsets for pCR in gastric cancer patients receiving preoperative chemotherapy remains unclear.

aimsThis study aims to assess the correlation between preoperative peripheral lymphocyte subsets and pCR in gastric cancer patients. METHODS AND

resultsIn this retrospective study, gastric cancer patients who underwent curative gastrectomy following preoperative chemotherapy were included. Cytokines and peripheral lymphocytes were measured using flow cytometry. Clinicopathological characteristics, peripheral lymphocyte data and cytokine data were collected for the analysis. Overall survival (OS) was analyzed using Kaplan-Meier curves. Of 173 patients, 15 (8.7%) achieved pCR. A lower proportion of CD19

conclusionsOur study indicated that a lower proportion of CD19

Indexed as

Antineoplastic Combined Chemotherapy ProtocolsLymphocyte SubsetsNeoadjuvant TherapyStomach NeoplasmsAdultAgedAntigens, CD19Chemotherapy, AdjuvantFemaleGastrectomyHumansKiller Cells, NaturalLymphocyte CountMaleMiddle AgedPathologic Complete ResponseAntigens, CD19CD19 molecule, humangastric cancerpathological complete responseperipheral lymphocyte subsetsystemic immunity

Identifiers

PMID42867008
PMCPMC13659800

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