ArticleTranslational andrology and urology2026
Is the density of transition zone prostate tissue truly 1 gram per milliliter?-an evaluation of HoLEP specimens.
Article in Translational andrology and urology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Prostate volume is assumed to equal prostate weight (PW), based on a 1:1 conversion between the milliliter (mL) and gram (g). While the 1:1 conversion holds for pure water, the density of transitional zone prostate tissue has not been studied. The aim of this study was to evaluate prostate density (PD) and the factors that affect it. Methods: This was an experimental Results: Specimen data were collected from 50 consecutive HoLEP patients, of whom 45 had complete data. Median resected intraoperative PW was 71 g (IQR, 56-89). Intraoperatively measured prostate volume was 74.2 mL (IQR, 60-89.6). Calculated PD was 0.95 (0.92-0.98). Prostate volume modestly overestimated resected PW by 3.35 mL (95% confidence interval: 1.10-5.35 Conclusions: In transitional zone prostate tissue collected from HoLEP specimens, PW was largely consistent with prostate volume, supporting the notion of 1:1 conversion. However, this did not hold for larger prostates, which were denser and exhibited greater variation in prostate volume. Correlation between PD and pathology needs to be further studied.
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