Evidence map›Paper›PMID 42866711›Full record

ArticleIBRO neuroscience reports2026

Research landscape of neurodegenerative diseases and brain energy metabolism: A multi-database integrative analysis.

Chengxi Weng, Xiaomai Huang, Haochen Huang, Fang Ke, Lijuan Zhang, Fengping Xu, Xiaoli Lin

Abstract read
In one paragraph

Article in IBRO neuroscience reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chengxi WengDepartment of Neurology, Jianyang First Hospital, Nanping, China.
Xiaomai HuangDepartment of Cardiology, Nanping First Hospital Affiliated to Fujian Medical University, Nanping, China.
Haochen HuangChinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Fang KeDepartment of Neurology, Ningde Hospital of Traditional Chinese Medicine, Ningde, China.
Lijuan ZhangDepartment of Neurology, Jianyang First Hospital, Nanping, China.
Fengping XuDepartment of Neurology, Nanping First Hospital Affiliated to Fujian Medical University, Nanping, China.
Xiaoli LinDepartment of Neurology, Nanping First Hospital Affiliated to Fujian Medical University, Nanping, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Neurodegenerative diseases are characterized by the progressive degeneration or death of neurons and their myelin sheaths. Increasing evidence suggests that impaired brain energy metabolism is a fundamental mechanism underlying the pathogenesis of these disorders. Therefore, a comprehensive understanding of research trends in this field is essential. Methods: A bibliometric analysis was conducted using merged and deduplicated data retrieved from the Web of Science Core Collection(WoSCC) and Scopus databases. Publications from 2004 to 2024 related to neurodegenerative diseases and brain energy metabolism were systematically analyzed. Key parameters included publication trends, and contributions from countries, institutions, journals, authors, references, and keywords. Results: A total of 3639 publications were identified, showing an overall increasing trend over the past two decades. These studies involved contributions from 54 countries or regions and were published across 459 academic journals. The United States and Italy were the leading contributors in this field. Keyword analysis revealed an evolution in research focus, with "microglia," "inflammation," and "cognitive decline" emerging as prominent and rapidly developing topics in recent years. Conclusion: This study provides a comprehensive overview of global research trends in brain energy metabolism in neurodegenerative diseases over the past 20 years. It highlights emerging hotspots and suggests potential future research directions, offering valuable insights for advancing this field.

Indexed as

Bibliometric analysisBrain energy metabolismCiteSpaceNeurodegenerative diseasesVOSviewer

Identifiers

PMID42866711
PMCPMC13657352

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.