Evidence map›Paper›PMID 42866694›Full record

ArticleiScience2026

Decoding how RNase E membrane targeting controls RNA degradosome activity in

Sandra Amandine Marie Geslain, George Edward Allen, Johan Geiser, Peter Redder, Martina Valentini

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sandra Amandine Marie GeslainDepartment of Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, 1211 Geneva, Switzerland.
George Edward AllenDepartment of Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, 1211 Geneva, Switzerland.
Johan GeiserDepartment of Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, 1211 Geneva, Switzerland.
Peter RedderLaboratoire de Microbiologie et Génétique Moléculaires (LMGM), Centre de Biologie Intégrative (CBI), Université Toulouse III, CNRS, 31400 Toulouse, France.
Martina ValentiniDepartment of Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, 1211 Geneva, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In many Proteobacterial species, transcription and RNA degradation are physically separated through segregation of the main ribonucleolytic machinery-the RNA degradosome-into RNase E-driven membrane-anchored assemblies that form discrete foci. Despite widespread conservation of the amphipathic membrane-targeting sequence (MTS) in RNase E, its function and biological importance remain poorly understood. Here, we have investigated how the MTS contributes to bacterial virulence or stress response in

Indexed as

amphipathic helixgram-negative bacteriaPseudomonas aeruginosaRNA degradosomeRNA localizationRNase E

Identifiers

PMID42866694
PMCPMC13657362

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.