ArticleOphthalmology science2026
Peripheral Vascular Alterations in
Article in Ophthalmology science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
11 authors.
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Abstract
Objective: To characterize peripheral retinal vascular alterations in Design: Cross-sectional observational study. Participants: Thirty eyes of 30 patients with genetically confirmed Methods: We performed complete ophthalmologic examination and multimodal retinal imaging, including fundus autofluorescence (FAF), OCT, OCTA, AF-based macular pigment optical density, and 130° WF-OCTA. A quantitative WF-OCTA analysis pipeline was developed to assess peripheral perfusion through concentric fovea-centered retinal rings. The Concentric Peripheral Perfusion Index, peripheral perfusion loss gradient, and perfusion profile slope were calculated. Associations between peripheral vascular status and central retinal imaging biomarkers were analyzed. Main Outcome Measures: WF-OCTA perfusion quantitative metrics. Results: Compared with controls, RP eyes showed significantly lower WF-OCTA perfusion indices across all eccentricity rings (all Conclusions: Financial Disclosures: Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.
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