Evidence map›Paper›PMID 42866675›Full record

ArticleiScience2026

Domain-autonomous MKLP1 modules divergently regulate mitotic fidelity and polyploidy in a holocentric system.

Bing Zhang, Xiao-Ning Liu, Mei-Ting Song, Meng-Fan Qin, Shu-Shu Tian, Yu Lin, Dan-Dan Li, Lun-Guang Yao, Camilo Ayra-Pardo, Yun-Chao Kan

Abstract read
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Bing ZhangHenan Key Laboratory of Insect Biology, Henan International Joint Laboratory of Insect Biology, College of Life Science, Nanyang Normal University, 1638 Wolong Road, Nanyang, Henan 473061, China.
Xiao-Ning LiuHenan Key Laboratory of Insect Biology, Henan International Joint Laboratory of Insect Biology, College of Life Science, Nanyang Normal University, 1638 Wolong Road, Nanyang, Henan 473061, China.
Mei-Ting SongHenan Key Laboratory of Insect Biology, Henan International Joint Laboratory of Insect Biology, College of Life Science, Nanyang Normal University, 1638 Wolong Road, Nanyang, Henan 473061, China.
Meng-Fan QinHenan Key Laboratory of Insect Biology, Henan International Joint Laboratory of Insect Biology, College of Life Science, Nanyang Normal University, 1638 Wolong Road, Nanyang, Henan 473061, China.
Shu-Shu TianHenan Key Laboratory of Insect Biology, Henan International Joint Laboratory of Insect Biology, College of Life Science, Nanyang Normal University, 1638 Wolong Road, Nanyang, Henan 473061, China.
Yu LinHenan Key Laboratory of Insect Biology, Henan International Joint Laboratory of Insect Biology, College of Life Science, Nanyang Normal University, 1638 Wolong Road, Nanyang, Henan 473061, China.
Dan-Dan LiHenan Key Laboratory of Insect Biology, Henan International Joint Laboratory of Insect Biology, College of Life Science, Nanyang Normal University, 1638 Wolong Road, Nanyang, Henan 473061, China.
Lun-Guang YaoHenan Key Laboratory of Insect Biology, Henan International Joint Laboratory of Insect Biology, College of Life Science, Nanyang Normal University, 1638 Wolong Road, Nanyang, Henan 473061, China.
Camilo Ayra-PardoCIIMAR/CIMAR LA, Interdisciplinary Centre of Marine and Environmental Research, University of Porto, Terminal de Cruzeiros Do Porto de Leixões, Avda. General Norton de Matos S/n, 4450-208 Matosinhos, Portugal.
Yun-Chao KanHenan Key Laboratory of Insect Biology, Henan International Joint Laboratory of Insect Biology, College of Life Science, Nanyang Normal University, 1638 Wolong Road, Nanyang, Henan 473061, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While the kinesin MKLP1 is a well-established regulator of cytokinesis, whether its individual domains possess autonomous functions has remained unexplored. Here, using the holocentric

Indexed as

Bombyx moricytokinesismitosisMKLP1spindle assembly

Identifiers

PMID42866675
PMCPMC13657243

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.