Evidence map›Paper›PMID 42866664›Full record

ArticleiScience2026

Proteomic and functional profiling of suspended jejunal enteroids reveals pharmacokinetic fidelity to native intestine.

Foteini Tzioufa, Merve Ceylan, Maria Letizia Di Martino, Dinh Son Vo, Ana C C Lopes, Rebekkah Hammar, Magnus Sundbom, Martin Skogar, Per M Hellström, Dominic-Luc Webb and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Foteini TzioufaDepartment of Pharmacy, Uppsala University, 752 37 Uppsala, Sweden.
Merve CeylanDepartment of Pharmacy, Uppsala University, 752 37 Uppsala, Sweden.
Maria Letizia Di MartinoDepartment of Medical Biochemistry and Microbiology, Uppsala University, 752 37 Uppsala, Sweden.
Dinh Son VoDepartment of Pharmacy, Uppsala University, 752 37 Uppsala, Sweden.
Ana C C LopesDepartment of Medical Biochemistry and Microbiology, Uppsala University, 752 37 Uppsala, Sweden.
Rebekkah HammarDepartment of Pharmacy, Uppsala University, 752 37 Uppsala, Sweden.
Magnus SundbomDepartment of Surgical Sciences, Uppsala University, 751 85 Uppsala, Sweden.
Martin SkogarDepartment of Surgical Sciences, Uppsala University, 751 85 Uppsala, Sweden.
Per M HellströmDepartment of Medical Sciences, Uppsala University, 751 85 Uppsala, Sweden.
Dominic-Luc WebbDepartment of Medical Sciences, Uppsala University, 751 85 Uppsala, Sweden.
Maria KarlgrenDepartment of Pharmacy, Uppsala University, 752 37 Uppsala, Sweden.
Iain GardnerCertara UK Ltd, Simcyp Division, Level 2-Acero, Sheffield S1 2BJ, UK.
Patrik LundquistDepartment of Pharmacy, Uppsala University, 752 37 Uppsala, Sweden.
Jens ErikssonDepartment of Medical Biochemistry and Microbiology, Uppsala University, 752 37 Uppsala, Sweden.
Daisy HjelmqvistDepartment of Pharmacy, Uppsala University, 752 37 Uppsala, Sweden.
Mikael E SellinDepartment of Medical Biochemistry and Microbiology, Uppsala University, 752 37 Uppsala, Sweden.
Madlen HubertDepartment of Pharmacy, Uppsala University, 752 37 Uppsala, Sweden.
Per ArturssonDepartment of Pharmacy, Uppsala University, 752 37 Uppsala, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intestinal enteroids are "mini-guts" that recapitulate essential features of the intestinal epithelium

Indexed as

drug metabolismdrug transportenteroidshuman small intestinelive-cell microscopyPBPK modelingproteomics

Identifiers

PMID42866664
PMCPMC13657221

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.