ArticleFrontiers in surgery2026
Coronary artery calcium burden and metabolic indices in relation to arteriovenous fistula functionality and post-functionality failure.
Article in Frontiers in surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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5 authors.
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Abstract
Background: Autogenous arteriovenous fistula (AVF) is the preferred haemodialysis access, but functionality failure and subsequent post-functionality AVF failure remain common. Whether coronary artery calcium (CAC), a marker of systemic vascular calcification, is associated with either outcome is unclear; competing events are frequently ignored. Objective: To examine CAC and metabolic markers in relation to AVF functionality and post-functionality AVF failure. Methods: In this single-centre retrospective cohort, 645 patients with end-stage kidney disease underwent first-time radiocephalic AVF creation. The primary outcome was functionality failure ( Results: Independent predictors of functionality failure were age (subdistribution hazard ratio [SHR] 1.53, 95% confidence interval [CI] 1.22-1.93, Conclusions: Older age and higher CAC burden are independently associated with AVF functionality failure, whereas the strongest determinant of subsequent patency loss is the need for assisted functionality. Preoperative static markers discriminate moderately; postoperative haemodynamic parameters are likely required for individual risk prediction.
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