Evidence map›Paper›PMID 42866477›Full record

ReviewGland surgery2026

Operative management of abdominal bulge following deep inferior epigastric perforator flap breast reconstruction: a systematic review of repair strategies and outcomes.

Raj Saini, Akshay Soni, Felicity Huang, Ishith Seth, Warren M Rozen

Abstract readReview
In one paragraph

Review in Gland surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Raj SainiFaculty of Health Sciences, Simon Fraser University, Burnaby, Canada.ORCID https://orcid.org/0009-0008-2480-7825
Akshay SoniDepartment of Plastic and Reconstructive Surgery, Peninsula University Hospital, Bayside Health, Melbourne, Australia.
Felicity HuangDepartment of Plastic and Reconstructive Surgery, St Vincent's Hospital Melbourne, The University of Melbourne, Melbourne, Australia.
Ishith SethDepartment of Plastic and Reconstructive Surgery, Peninsula University Hospital, Bayside Health, Melbourne, Australia.
Warren M RozenDepartment of Plastic and Reconstructive Surgery, Peninsula University Hospital, Bayside Health, Melbourne, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Abdominal bulge after deep inferior epigastric perforator (DIEP) flap breast reconstruction is an uncommon but clinically meaningful donor-site complication. Although several operative repair strategies have been described, evidence guiding management remains limited. This systematic review aimed to synthesize the evidence on operative management of established abdominal bulge after DIEP flap breast reconstruction, including repair techniques, outcomes, and persistent or recurrent deformity. Methods: This review was prospectively registered (PROSPERO CRD420261368586). MEDLINE, Scopus, and Web of Science were searched from inception to August 2026 for studies reporting abdominal wall morbidity after DIEP flap breast reconstruction and describing management of an established complication with extractable outcomes. Quality was appraised with Joanna Briggs Institute tools and certainty of evidence with GRADE. Heterogeneity in design, definitions, techniques, and outcome reporting precluded meta-analysis, so findings were synthesized narratively. Results: Six studies were included: five retrospective single-arm series and one case report, with no randomized, prospective comparative or controlled study identified. Clinically relevant bulge or hernia occurred in 3.6% to 4.8% of patients in cohorts reporting denominators. Repair outcomes were extractable for 34 patients across five studies, spanning DIEP-specific and mixed abdominal free-flap populations. Reported techniques were open fascial plication with onlay mesh, laparoscopic underlay, robotic retromuscular, and enhanced-view totally extraperitoneal repair. Persistent or recurrent deformity followed both open and minimally invasive approaches. Certainty was very low for every outcome assessed, and no study used a validated post-repair patient-reported outcome measure, objective abdominal wall function testing, or imaging-confirmed durability assessment. Conclusions: Operative management of post-DIEP abdominal bulge is poorly standardized, and very low certainty evidence does not establish superiority of any technique, mesh type, or mesh plane. We propose a phenotype-based classification, a structured assessment pathway, and a minimum reporting dataset for secondary repair, offered as expert interpretation requiring prospective validation rather than as guidance. Future studies should use standardized phenotyping, repair-specific follow-up, cross-sectional or dynamic imaging, objective function testing, and validated patient-reported outcomes.

Indexed as

abdominal bulgeabdominal wall morbiditybreast reconstructionDeep inferior epigastric perforator flap (DIEP flap)hernia repair

Identifiers

PMID42866477
PMCPMC13657785

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.