Evidence map›Paper›PMID 42866414›Full record

ArticleAlzheimer's & dementia (Amsterdam, Netherlands)

The 20-item Noise Pareidolia Task: normative data and performance in MCI-LB and DLB.

Tanis J Ferman, John A Lucas, Yoshiyuki Nishio, Jeremiah A Aakre, Neill R Graff-Radford, David S Knopman, Jonathan Graff-Radford, Julie A Fields, Paula A Aduen, Mary M Machulda and 8 more

Abstract read
In one paragraph

Article in Alzheimer's & dementia (Amsterdam, Netherlands). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Tanis J FermanDepartment of Psychiatry and Psychology Mayo Clinic Jacksonville Florida USA.
John A LucasDepartment of Psychiatry and Psychology Mayo Clinic Jacksonville Florida USA.
Yoshiyuki NishioDepartment of Behavioral Neurology and Neuropsychiatry Osaka University Osaka JAPAN.
Jeremiah A AakreDepartment of Biomedical Statistics and Informatics Mayo Clinic Rochester Minnesota USA.
Neill R Graff-RadfordDepartment of Neurology Mayo Clinic Jacksonville Florida USA.
David S KnopmanDepartment of Neurology Mayo Clinic Rochester Minnesota USA.
Jonathan Graff-RadfordDepartment of Neurology Mayo Clinic Rochester Minnesota USA.
Julie A FieldsDepartment of Psychiatry and Psychology Mayo Clinic Rochester Minnesota USA.
Paula A AduenDepartment of Psychiatry and Psychology Mayo Clinic Jacksonville Florida USA.
Mary M MachuldaDepartment of Psychiatry and Psychology Mayo Clinic Rochester Minnesota USA.
Rodolfo SavicaDepartment of Neurology Mayo Clinic Rochester Minnesota USA.
Christian LachnerDepartment of Neurology Mayo Clinic Jacksonville Florida USA.
Gregory S DayDepartment of Neurology Mayo Clinic Jacksonville Florida USA.
Stuart J McCarterDepartment of Neurology Mayo Clinic Rochester Minnesota USA.
Toji MiyagawaDepartment of Neurology Mayo Clinic Rochester Minnesota USA.
Ronald C PetersenDepartment of Neurology Mayo Clinic Rochester Minnesota USA.
Kejal KantarciDepartment of Radiology Mayo Clinic Rochester Minnesota USA.
Bradley F BoeveDepartment of Neurology Mayo Clinic Rochester Minnesota USA.

Funding

SUPPLEMENT TO ALZHEIMERS DISEASE PATIENT REGISTRYU01AG006786 · NIA · MAYO CLINIC ROCHESTER · PI GRAFF-RADFORD, JONATHAN, JACK, CLIFFORD R. · 1986 to 2023
$49.6M
Research Education ComponentP30AG062677 · NIA · MAYO CLINIC ROCHESTER · PI NILUFER ERTEKIN-TANER · 2019 to 2026
$33.5M
Longitudinal Imaging Biomarkers of Prodromal DLBU01NS100620 · NINDS · MAYO CLINIC ROCHESTER · PI Bradley F Boeve, KEJAL KANTARCI · 2017 to 2026
$19.2M
NIA NIH HHS P30 AG062677NIA NIH HHS U01 AG006786NINDS NIH HHS U01 NS100620
6 · The paper itself

Abstract

introductionVisual perceptual difficulties occur in dementia with Lewy bodies (DLB). Normative data and cut scores for DLB and mild cognitive impairment with Lewy bodies (MCI-LB) are needed for the 20-item Noise Pareidolia Task.

methodsParticipants included 344 cognitively unimpaired (CU), 112 DLB, and 105 MCI-LB. Cumulative percentile ranking was used for normative classification. Receiver operating characteristic analyses, convergent validity, and associations with visual hallucinations (VH) were assessed.

resultsIn CU participants, a perfect score was average, one error was low average, and two or more errors fell below average. A cut score of one or more errors optimally distinguished CU participants from DLB (Total score area under the curve [AUC]: 0.82, Noise score AUC: 0.77) and MCI-LB (Total score AUC: 0.75, Noise score AUC: 0.74). A cut score of two or more errors lowered sensitivity but increased specificity to 94%. Performance was associated with VH in DLB, but not MCI-LB. DISCUSSION: Results establish normative data for the 20-item Noise Pareidolia Task and support its use in DLB and MCI-LB.

Indexed as

hallucinationsillusionsLewy body dementiamild cognitive impairmentmisperceptionsneuropsychologicalnormsPareidolia

Identifiers

PMID42866414
PMCPMC13656198

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.