ArticleBioinformatics advances2026
BLITSFR: scalable comparative genomics with self-contained interactive single file report.
Article in Bioinformatics advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
3 authors.
Funding
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Abstract
Motivation: Comparative genomics routinely requires the alignment of query genomes against a reference to delineate conserved and variable regions, yet existing tools often produce static visualisations or necessitate centralised web services and data uploads. Results: To address this, we present BLITSFR (BLAST Interactive Tracks in Single-File Report), a command-line tool that compares query genomes against a reference and returns a single interactive HTML file. The report opens in any modern browser, requiring no server or data upload, and lets users explore conserved and variable regions across the genomes. BLITSFR handles both assembled genomes and raw reads, and processes hundreds of genomes in minutes on a standard laptop with genome tracks sorting, filtering, and colouring by metadata are performed within the report, without requirement for re-running the analysis. We demonstrate its utility by analysing vancomycin-resistant Availability and implementation: BLITSFR and SCIFR are freely available at the provided GitHub repositories (https://github.com/nalarbp/blitsfr, https://github.com/nalarbp/scifr).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.