ArticleIJID regions2026
Cysticercosis and neurocysticercosis in Eastern Zambia: A cross-sectional, community-based study.
Article in IJID regions, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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13 authors.
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Abstract
Objective: This study aimed to estimate the seroprevalence of cysticercosis and the prevalence of neurocysticercosis (NCC) among cysticercosis-positive participants, and to describe their clinical and radiological manifestations in rural Zambia. Methods: A cross-sectional study was conducted between June 2019 and December 2022 in the Eastern Province of Zambia. The serum antigen enzyme-linked immunosorbent assay (Ag-ELISA) and Cysticercosis immunoglobulin G (IgG) Western blot were used to detect cysticercosis. All cysticercosis (CC)-positive participants received further clinical work-up and cerebral computed tomography (CT) examination. Results: Out of 2876 serum samples examined, 70 (2.4%) [95% confidence interval (CI) = 1.9-3.1%] tested positive only on Ag-ELISA, 149 (5.2%) [95% CI = 4.4-6.1%] tested positive only on the Western blot and 35 (1.2%) [95% CI = 0.9-1.7%] were positive on both the antigen and antibody tests, yielding a total of 254 (8.8%) [95% CI = 7.8-9.9%] positive on at least one serological test. More males than females were CC-positive (10.6% versus 7.6%, Conclusion: Our findings demonstrate that cysticercosis and NCC are prevalent in this rural community in the Eastern Province of Zambia. Most of the patients with NCC had calcified lesions, and people with NCC more often had epileptic seizures and headache than those without NCC; only a few people had neurological deficits.
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