Evidence map›Paper›PMID 42866161›Full record

ArticleAnimal nutrition (Zhongguo xu mu shou yi xue hui)2026

Ursolic acid alleviates high starch induced hepatic glucose and lipid metabolism disorders in largemouth bass (

Xiwen Zhang, Ming Wang, Shuang Wu, Qi Luo, Shuning Jin, Xiang Li, Yue Yin, Yongfang Wang, Yurong Zhao, Hongquan Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Animal nutrition (Zhongguo xu mu shou yi xue hui), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xiwen ZhangCollege of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, Hunan, China.
Ming WangCollege of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, Hunan, China.
Shuang WuCollege of Fisheries, Hunan Agricultural University, Changsha 410128, Hunan, China.
Qi LuoCollege of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, Hunan, China.
Shuning JinCollege of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, Hunan, China.
Xiang LiCollege of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, Hunan, China.
Yue YinCollege of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, Hunan, China.
Yongfang WangHengnan County Agriculture and Rural Affairs Bureau, Hengyang 420000, China.
Yurong ZhaoCollege of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, Hunan, China.
Hongquan WangCollege of Fisheries, Hunan Agricultural University, Changsha 410128, Hunan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Disorders of hepatic glucose and lipid metabolism are a significant factor reducing the economic value of largemouth bass. Ursolic acid (UA) has been shown to regulate such metabolic disorders. This study aimed to investigate the core mechanism of UA in hepatic glucose and lipid metabolism in largemouth bass fed a high starch (HS) diet. A total of 800 healthy largemouth bass with an initial average body weight of 11.00 ± 0.12 g were selected and randomly allocated into four treatment groups in a 2 × 2 factorial design: control (CON) group, UA group, HS group, and HS + UA group. Each group had five replicates with 40 fish per replicate. Fish in the CON group received a basal diet (7.38% starch); the UA group received the basal diet supplemented with UA at 500 mg/kg; the HS group received the HS diet (13.26% starch); and the HS + UA group received the HS diet supplemented with UA at 500 mg/kg. The experiment lasted for 8 weeks. To further validate the direct regulatory effect of UA on the CERK/PI3K/AKT signaling pathway in hepatocytes, this study established an in vitro primary hepatocyte culture model containing five groups: CON, high-glucose (HG), HG + UA, HG + NVP231 (CERK inhibitor), and HG + UA + NVP231. Results showed that the HS diet led to reduced final weight, weight gain ratio and body crude protein content, increased body ether extract content and hepatic collagen area (

Indexed as

Glucose metabolismHigh starchLargemouth bassLipid metabolismUrsolic acid

Identifiers

PMID42866161
PMCPMC13656957

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.