Evidence map›Paper›PMID 42866157›Full record

ArticleVeterinary and animal science2026

Long-term dietary pyrroloquinoline quinone (PQQ) supplementation on growth, immune response, and antioxidant status in juvenile stellate sturgeon (

Seyed Hossein Hoseinifar, Hamed Vardastzadeh, Mostafa Beygi, Majid Khanzadeh, Hien Van Doan

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Article in Veterinary and animal science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

5 authors.

Seyed Hossein HoseinifarDepartment of Fisheries, Faculty of Fisheries and Environmental Sciences, Gorgan University of Agricultural Sciences and Natural Resources, Gorgan, , Iran.
Hamed VardastzadehDepartment of Fisheries, Faculty of Fisheries and Environmental Sciences, Gorgan University of Agricultural Sciences and Natural Resources, Gorgan, , Iran.
Mostafa BeygiDepartment of Fisheries, Faculty of Fisheries and Environmental Sciences, Gorgan University of Agricultural Sciences and Natural Resources, Gorgan, , Iran.
Majid KhanzadehDepartment of Fisheries, Faculty of Fisheries and Environmental Sciences, Gorgan University of Agricultural Sciences and Natural Resources, Gorgan, , Iran.
Hien Van DoanDepartment of Animal and Aquatic Sciences, Faculty of Agriculture, Chiang Mai University, Chiang Mai, 50200, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to evaluate the effects of dietary pyrroloquinoline quinone (PQQ) on growth performance, immune responses, and antioxidant status in juvenile stellate sturgeon (Acipenser stellatus). A total of 120 juvenile sturgeons (121.02 ± 5.91 g) were randomly distributed into four groups, each with three replicates, including a control diet without PQQ and three experimental diets supplemented with 1.5, 3, and 4.5 mg/kg PQQ for 86 days. Following the feeding trial, growth performance was evaluated, and immune markers in both serum and mucus were analyzed, along with serum antioxidant enzyme activities. The results showed that the diet containing 3 and 4.5 mg/kg PQQ significantly improved growth parameters compared to the control group (P < 0.05). Immune indicators, particularly serum and mucus lysozyme activity (in serum of all groups and mucus of group 3 mg/kg) and total immunoglobulin (3 and 4.5 mg/kg) levels, were significantly enhanced in PQQ-supplemented groups (P < 0.05). ACH50 activity was significantly increased in all groups compared to the control group (P < 0.05). A significant increase in soluble mucus protein was observed at 3 and 4.5 mg/kg compared to the control group. Furthermore, PQQ supplementation markedly improved SOD activity across all doses, increased CAT activity at 3 and 4.5 mg/kg, and modulated GPx activity at 1.5 and 3 mg/kg. These results demonstrate that dietary PQQ effectively enhances immune function and growth, leading to improved health and production in juvenile stellate sturgeon.

Indexed as

Acipenser stellatusAntioxidantGrowth parametersInnate immunityPyrroloquinoline quinone

Identifiers

PMID42866157
PMCPMC13656953

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.