ArticleFrontiers in nutrition2026
Association between dietary branched-chain amino acid intake and anaemia risk in children and adolescents: a matched case-control study.
Article in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Anaemia in children and adolescents is multifactorial, and evidence on dietary amino-acid intake in relation to anaemia remains limited. This study examined the association between dietary branched-chain amino acid (BCAA) intake and haemoglobin (Hb)-defined anaemia among Chinese children and adolescents using data from the 2016-2019 China Children and Lactating Women Nutrition and Health Survey. Among 11,134 eligible participants aged 6-17 years, quantile g-computation and the Boruta algorithm were first used to screen 20 dietary amino acids. A 1:4 propensity score-matched sample was then constructed, including 455 participants with anaemia and 1,819 with normal Hb levels. Dietary BCAA intake and its components, isoleucine (Ile), leucine (Leu) and valine (Val), were energy-adjusted using the residual method. Machine learning methods were used exploratorily for feature ranking, and conditional logistic regression was used to estimate odds ratios (ORs). After matching, total dietary protein intake was comparable between groups, whereas intakes of total BCAA, Ile, Leu, and Val were significantly lower in the anaemia group. In fully adjusted models, higher intakes of total BCAA, Ile, Leu, and Val were associated with lower odds of Hb-defined anaemia, with ORs of 0.95 (95% CI: 0.92-0.99), 0.82 (95% CI: 0.70-0.95), 0.91 (95% CI: 0.85-0.98) and 0.86 (95% CI: 0.78-0.95), respectively. Supplementary biomarker analyses showed lower ferritin and higher soluble transferrin receptor concentrations in the anaemia group, whereas high-sensitivity C-reactive protein did not differ between groups. These findings suggest that BCAA-related dietary characteristics may provide useful nutritional clues for anaemia-related assessment, although the association should not be interpreted as evidence of a BCAA-specific protective effect.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.