Evidence map›Paper›PMID 42866044›Full record

ArticleFrontiers in psychiatry2026

Trait, state, and behavior in adolescent NSSI addiction: a serial mediation model linking childhood trauma to NSSI addiction.

Lan Hu, Feiyan Wang, Li Pu, Guojian Yan, Yunge Li

Abstract read
In one paragraph

Article in Frontiers in psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Lan HuThe Clinical Hospital of Chengdu Brain Science Institute, MOE Key Lab for Neuroinformation, University of Electronic Science and Technology of China, Chengdu, China.
Feiyan WangThe Clinical Hospital of Chengdu Brain Science Institute, MOE Key Lab for Neuroinformation, University of Electronic Science and Technology of China, Chengdu, China.
Li PuThe Clinical Hospital of Chengdu Brain Science Institute, MOE Key Lab for Neuroinformation, University of Electronic Science and Technology of China, Chengdu, China.
Guojian YanThe Clinical Hospital of Chengdu Brain Science Institute, MOE Key Lab for Neuroinformation, University of Electronic Science and Technology of China, Chengdu, China.
Yunge LiThe Clinical Hospital of Chengdu Brain Science Institute, MOE Key Lab for Neuroinformation, University of Electronic Science and Technology of China, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Despite growing recognition of non-suicidal self-injury (NSSI) as a potential behavioral addiction, the sequential mechanisms linking childhood trauma to NSSI addiction remain unclear. This study examined a serial mediation model testing whether trait impulsivity and depressive symptoms sequentially mediate this relationship, with NSSI function as a behavioral coping mechanism. Methods: This cross-sectional study included 163 Chinese adolescents diagnosed with major depressive disorder and a history of NSSI. Participants completed the Childhood Trauma Questionnaire-Short Form, the Short UPPS-P Impulsive Behavior Scale, the Children's Depression Inventory, and the Ottawa Self-Injury Inventory (Functions and Addictive Features subscales). Serial mediation analysis (PROCESS Model 6, 5,000 bootstrap resamples), controlling for demographic and clinical covariates, tested the hypothesized five-step sequential model. Results: Childhood trauma was positively associated with NSSI addiction, and this association was predominantly mediated: the total indirect effect accounted for 56.2% of the total effect. Indirect effects involving NSSI function in combination with upstream mediators were significant, including the full sequential path (B = 0.0033, 95% CI [0.0007, 0.0083]), whereas simple mediations via impulsivity, depression, or NSSI function alone were not. Conclusion: These findings support a trait-state-behavior-addiction cascade in which childhood trauma is associated with trait impulsivity and depressive symptoms that, in combination with the reinforcing function of NSSI, are linked to addictive features of NSSI. The model advances theoretical understanding of NSSI addiction and offers actionable clinical targets for prevention and intervention. Longitudinal studies are needed to confirm causal directions.

Indexed as

addictive behaviorchildhood traumadepressionimpulsivitynonsuicidal self-injurious behavior

Identifiers

PMID42866044
PMCPMC13655704

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