Evidence map›Paper›PMID 42866041›Full record

ArticleBJA open2026

Effect of intraoperative high positive end-expiratory pressure with recruitment manoeuvres

Damien Rousseleau, Thomas Bluth, Bas Bruneel, Matti Slabbaert, Ary Serpa Neto, Marcus J Schultz, Marcelo Gama de Abreu, Luc De Baerdemaeker, PROBESE Investigators, Protective Ventilation Network, and the Clinical Trials Network of the European Society of Anaesthesiology and Intensive Care

Registry-linked trialAbstract read
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In one paragraph

Article in BJA open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02148692 (Protective Ventilation With Higher Versus Lower PEEP During General Anesthesia for Surgery in Obese Patients), which is not on this map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02148692 nacompletednot on this map

Protective Ventilation With Higher Versus Lower PEEP During General Anesthesia for Surgery in Obese Patients

TypeinterventionalSponsorTechnische Universität DresdenRan2014 to 2018Enrolled2,013ConditionsMorbid Obesity, Surgery, General AnesthesiaArmsHigher PEEP, Lower PEEP
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Damien RousseleauDepartment of Anaesthesiology and Perioperative Medicine, Ghent University Hospital, Ghent, Belgium.
Thomas BluthDepartment of Anesthesiology and Intensive Care Medicine, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany.
Bas BruneelDepartment of Anaesthesiology and Perioperative Medicine, Ghent University Hospital, Ghent, Belgium.
Matti SlabbaertDepartment of Anaesthesiology and Perioperative Medicine, Ghent University Hospital, Ghent, Belgium.
Ary Serpa NetoAustralian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.
Marcus J SchultzDivision of Cardiothoracic and Vascular Anaesthesia and Critical Care Medicine, Department of Anaesthesia, General Intensive Care and Pain Management, Medical University Wien, Vienna, Austria.
Marcelo Gama de AbreuDepartment of Anesthesiology and Intensive Care Medicine, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany.
Luc De BaerdemaekerDepartment of Anaesthesiology and Perioperative Medicine, Ghent University Hospital, Ghent, Belgium.
PROBESE Investigators, Protective Ventilation Network, and the Clinical Trials Network of the European Society of Anaesthesiology and Intensive Care

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Patients with obesity are at an increased risk of postoperative pulmonary complications and impaired lung function after general anaesthesia. Although higher levels of PEEP combined with recruitment manoeuvres may improve intraoperative respiratory mechanics, their effect on postoperative lung function remains uncertain. We evaluated whether high PEEP with recruitment manoeuvres improves postoperative spirometry in obese patients undergoing abdominal surgery. Methods: This single-centre substudy of the Protective Ventilation in Obese Patients randomised controlled trial was conducted at Ghent University Hospital, Belgium. Adults with a BMI of ≥35 kg·m Results: Postoperative spirometry data were available for 44 patients (23 low PEEP, 21 high PEEP). Postoperative lung function declined in all patients. The change in FEV Conclusions: In obese patients undergoing abdominal surgery with low tidal volume ventilation, high PEEP with recruitment manoeuvers did not improve postoperative spirometric outcomes or oxygen saturation compared with low PEEP without routine recruitment manoeuvres. Trial registration: ClinicalTrials.gov, NCT02148692.

Indexed as

mechanical ventilationobesityPEEPpostoperative complicationspulmonary function testsspirometry

Identifiers

PMID42866041
PMCPMC13656559

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