Evidence map›Paper›PMID 42865976›Full record

ArticleInternational journal of reproductive biomedicine2026

Comparison of indomethacin and nifedipine regarding ductus arteriosus Doppler findings after laser therapy for monochorionic diamniotic twin-to-twin transfusion syndrome: A retrospective cohort study.

Sareh Mokhtari, Laleh Eslamian, Vajiheh Marsoosi, Alireza Golbabaei, Nafiseh Saedi, Paria Boustani

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Article in International journal of reproductive biomedicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Sareh MokhtariDepartment of Obstetrics and Gynecology, Tehran University of Medical Sciences, Tehran, Iran.
Laleh EslamianDepartment of Obstetrics and Gynecology, Tehran University of Medical Sciences, Tehran, Iran.
Vajiheh MarsoosiDepartment of Obstetrics and Gynecology, Tehran University of Medical Sciences, Tehran, Iran.
Alireza GolbabaeiDepartment of Perinatology and Fetal Cardiology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Nafiseh SaediDepartment of Obstetrics and Gynecology, Yas Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Paria BoustaniDigestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Indomethacin is administered to reduce preterm labor after fetoscopic laser photocoagulation (FLP) of placental anastomoses. Objective: To compare ductus arteriosus (DA) Doppler findings in monochorionic diamniotic twin pregnancies complicated by twin-to-twin transfusion syndrome following FLP between cases treated with indomethacin and those treated with nifedipine. Materials and Methods: In this retrospective cohort study, data of 86 pregnant women aged 17-41 yr who underwent FLP in Shariati hospital, Tehran, Iran from October 2024-November 2025 were extracted from medical records and then followed up. In the study, based on pulse rate, the cases were placed in one of 2 groups: nifedipine (pulse rate Results: Peak systolic velocity was higher in both donor (145.7 Conclusion: DA constriction is associated with significant changes in blood flow indices, a higher incidence of right ventricular dysfunction, and a greater prevalence of valvular regurgitation. In this study, fetal DA constriction resolved during the short-term follow-up period.

Indexed as

Doppler echocardiographyDuctus arteriosusFetofetal transfusionLaser therapy.

Identifiers

PMID42865976
PMCPMC13655624

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