ArticleFrontiers in neuroscience2026
Analytical validation of digital measure of intelligibility in progressive supranuclear palsy.
Article in Frontiers in neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: Progressive supranuclear palsy (PSP) causes progressive speech impairment. Digital speech analysis can objectively and remotely quantify measures like intelligibility, typically judged subjectively by experts during clinical visits. The objective of this study is to validate digital intelligibility measurement in PSP via BioDigit Speech (BioSensics LLC, United States). Methods: Forty-nine PSP patients performed standardized passage-reading scored by BioDigit Speech and three experts (18 + years of experience); expert mean score (EMS) served as the reference standard. Results: Digital intelligibility showed high correlation and agreement with EMS ( Conclusion: Collected remotely with minimal burden, digital speech measures like intelligibility may serve as objective, sensitive outcomes for communication-focused interventions and PSP trials.
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