Evidence map›Paper›PMID 42865489›Full record

ArticleFrontiers in stroke2026

Electrophysiological signature of stroke recovery: investigating EEG biomarkers for prognostic insights.

Majid Khalili-Ardali, Vivek Sharma, Tarandeep Singh Mandahar, Francisco Páscoa Dos Santos, Paul Tiesinga, Nick Ramsey

Abstract read
In one paragraph

Article in Frontiers in stroke, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Majid Khalili-Ardali *Donders Institute for Brain, Cognition, and Behaviour, Radboud University, Nijmegen, Netherlands.
Vivek Sharma *Donders Institute for Brain, Cognition, and Behaviour, Radboud University, Nijmegen, Netherlands.
Tarandeep Singh MandaharDonders Institute for Brain, Cognition, and Behaviour, Radboud University, Nijmegen, Netherlands.
Francisco Páscoa Dos SantosCognitive and Systems Neuroscience Group, Swammerdam Institute for Life Sciences, Faculty of Science, University of Amsterdam, Amsterdam, Netherlands.
Paul TiesingaDonders Institute for Brain, Cognition, and Behaviour, Radboud University, Nijmegen, Netherlands.
Nick RamseyDonders Institute for Brain, Cognition, and Behaviour, Radboud University, Nijmegen, Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Stroke is a leading cause of long-term disability, often resulting in persistent motor impairments that reflect disruptions in large-scale brain networks. An integrated framework capturing spatiotemporal EEG dynamics would help clarify how these networks change during recovery. Methods: We analysed resting-state EEG from stroke patients at 1 week (Session 1) and three months (Session 2) post-stroke to investigate electrophysiological biomarkers of motor recovery, indexed by change in the Fugl-Meyer scale (Δ Resultss: Change in relative alpha power emerged as the strongest single correlate of motor improvement, accounting for the largest proportion of variance among the EEG measures examined. Metastability and synchrony did not individually reach statistical significance but showed moderate positive correlations with Δ Discussion: These findings indicate that stroke recovery involves restoring balanced alpha oscillations and flexible large-scale brain coordination. Larger samples and more frequent longitudinal assessments are required to confirm the prognostic utility of integrated EEG biomarkers for guiding personalised stroke rehabilitation strategies.

Indexed as

EEGlesionmetastabilitymicrostatesstrokesynchrony

Identifiers

PMID42865489
PMCPMC13654781

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.