Evidence map›Paper›PMID 42865147›Full record

ArticleThe breast journal2026

Dosimetric Comparison of Five Radiotherapy Techniques in Left-Sided Breast Cancer Patients Following Breast-Conserving Surgery.

Yanqiu Zhang, A'meng Han, Sen Yang, Jianxin Zhao, Xiumei Li

Abstract readComparative Study
In one paragraph

Article in The breast journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yanqiu ZhangDepartment of Radiotherapy, First Hospital of Qinhuangdao, Qinhuangdao, 066000, Hebei, China, qhdsdyyy.com.ORCID https://orcid.org/0000-0002-8444-0040
A'meng HanState Key Laboratory of Metastable Materials Science and Technology, Yanshan University, Qinhuangdao, 066004, Hebei, China, ysu.edu.cn.ORCID https://orcid.org/0009-0005-6064-438X
Sen YangDepartment of Radiotherapy, First Hospital of Qinhuangdao, Qinhuangdao, 066000, Hebei, China, qhdsdyyy.com.ORCID https://orcid.org/0009-0009-2415-2379
Jianxin ZhaoDepartment of Radiotherapy, First Hospital of Qinhuangdao, Qinhuangdao, 066000, Hebei, China, qhdsdyyy.com.ORCID https://orcid.org/0009-0002-0048-9929
Xiumei LiDepartment of Radiotherapy, First Hospital of Qinhuangdao, Qinhuangdao, 066000, Hebei, China, qhdsdyyy.com.ORCID https://orcid.org/0009-0002-7453-7241

Funding

Health Commission of Hebei Province 20181196
6 · The paper itself

Abstract

objectiveThis study aims to compare and evaluate the dosimetric characteristics of five radiotherapy techniques in left-sided breast cancer patients following breast-conserving surgery. The five radiotherapy techniques include three-dimensional conformal radiation therapy (3D-CRT), fixed-field intensity-modulated radiation therapy (ff-IMRT), volumetric modulated arc therapy (VMAT), hybrid 3D-CRT with IMRT (CRT + IMRT), and hybrid 3D-CRT with VMAT (CRT + VMAT). PATIENTS AND

methodsTen patients with left-sided breast cancer who received postlumpectomy radiotherapy at the Department of Radiation Oncology, First Hospital of Qinhuangdao, between June 1, 2020, and June 1, 2021, were randomly enrolled in this study. For each patient, five distinct treatment plans were designed using the five aforementioned techniques (3D-CRT, ff-IMRT, VMAT, CRT + IMRT, and CRT + VMAT) based on identical computed tomography (CT) imaging datasets. Dosimetric parameters for the tumor target volume, organs at risk (OARs), and normal tissues (defined as body minus planning target volume [PTV], termed B-P) were analyzed and compared using dose-volume histograms (DVHs) and isodose distributions.

resultsThe CRT + VMAT technique demonstrated superior PTV dose coverage, conformity, and homogeneity compared to 3D-CRT, ff-IMRT, VMAT, and CRT + IMRT (p < 0.05). In contrast, the VMAT technique achieved significantly lower V

conclusionClinicians may tailor radiotherapy plans to individual patients based on the distinct dosimetric profiles of each technique. For patients requiring optimal PTV dose distribution, the CRT + VMAT technique is suggest. For enhanced cardiopulmonary protection (e.g., reduced lung/heart doses), ff-IMRT or CRT + IMRT may be prioritized. Additionally, 3D-CRT should be the first choice for patients needing rapid fractionated treatment due to its efficiency in minimizing MUs and treatment time.

Indexed as

Unilateral Breast NeoplasmsAdultAgedFemaleHumansMastectomy, SegmentalMiddle AgedOrgans at RiskRadiometryRadiotherapy, ConformalRadiotherapy DosageRadiotherapy, Intensity-ModulatedRadiotherapy Planning, Computer-Assistedbreast-conserving surgery cancer patientsCRTCRT + IMRTCRT + VMATdosimetricIMRTVMAT

Identifiers

PMID42865147
PMCPMC13659263

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.