Evidence map›Paper›PMID 42865079›Full record

ArticleAmerican journal of human biology : the official journal of the Human Biology Council2026

Study Protocol for the Daasanach Human Biology Project: A Longitudinal Study of the Impact of Drinking Water Salinity and Heat Stress on Water Insecurity, Hydration, Energetics, Hypertension, and Kidney Function in Northern Kenya.

Alfredo J Rojas, Emmanuel Ndiema, Rosemary Nzunza, Michael Hunter, Jeff M Sands, William Farquhar, W Larry Kenney, Kedir Teji Roba, Amanda McGrosky, Matthew Douglass and 2 more

Abstract read
In one paragraph

Article in American journal of human biology : the official journal of the Human Biology Council, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Alfredo J RojasDepartment of Biobehavioral Health, Pennsylvania State University, University Park, Pennsylvania, USA.ORCID https://orcid.org/0000-0002-0729-2953
Emmanuel NdiemaDepartment of Earth Sciences, National Museums of Kenya, Nairobi, Kenya.ORCID https://orcid.org/0000-0002-1335-2924
Rosemary NzunzaCenter for Virus Research, Kenya Medical Research Institute (KEMRI), Nairobi, Kenya.
Michael HunterDepartment of Human Development and Family Studies, Pennsylvania State University, University Park, Pennsylvania, USA.ORCID https://orcid.org/0000-0002-3651-6709
Jeff M SandsSchool of Medicine, Emory University, Atlanta, Georgia, USA.ORCID https://orcid.org/0000-0001-9822-0607
William FarquharDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, Delaware, USA.
W Larry KenneyDepartment of Kinesiology, Pennsylvania State University, University Park, Pennsylvania, USA.
Kedir Teji RobaDepartment of Biobehavioral Health, Pennsylvania State University, University Park, Pennsylvania, USA.
Amanda McGroskyDepartment of Biology, Elon University, Elon, North Carolina, USA.ORCID https://orcid.org/0000-0002-1110-4310
Matthew DouglassCollege of Agricultural Sciences and Natural Resources, University of Nebraska-Lincoln, Lincoln, Nebraska, USA.
Herman PontzerDepartment of Evolutionary Anthropology, Duke University, Durham, North Carolina, USA.ORCID https://orcid.org/0000-0003-2397-6543
Asher Y RosingerDepartment of Biobehavioral Health, Pennsylvania State University, University Park, Pennsylvania, USA.ORCID https://orcid.org/0000-0001-9587-1447

Funding

STALLARD Admin Supp: Predicting Future Care Needs and Costs for Individual Medicare Enrollees with Incident Suspected Alzheimer's DiseaseP30AG034424 · NIA · DUKE UNIVERSITY · PI SCOTT M. LYNCH · 2009 to 2026
$12.2M
The Population Research Institute: Development CoreP2CHD041025 · NICHD · PENNSYLVANIA STATE UNIVERSITY, THE · PI Brian Thiede · 2016 to 2026
$9.0M
Drinking water salinity in a hot-dry environment: Hydration, kidney function, and blood pressureR01ES035402 · NIEHS · PENNSYLVANIA STATE UNIVERSITY, THE · PI Asher Y. Rosinger · 2024 to 2026
$2.1M
National Institute of Environmental Health Science (NIEHS) R01ES035402National Institute on Aging (NIA) P30 AG034424National Science Foundation 1852406National Science Foundation 1924322NIA NIH HHS P30 AG034424NICHD NIH HHS P2C HD041025NIEHS NIH HHS R01 ES035402NIH's Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) P2CHD041025Penn State University
6 · The paper itself

Abstract

introductionIncreasing salinity of groundwater is a global environmental health threat that has been overlooked in human biology and may increase the risk of water insecurity, dehydration, chronic kidney disease (CKD), and hypertension in humans. However, no health standards exist for salinity levels in drinking water. This protocol paper describes the Daasanach Human Biology Project, which is testing how water salinity exposure and heat stress impact hydration, kidney disease, and blood pressure among Daasanach pastoralists in a hot-arid environment in northern Kenya. METHODS/

designThis study expands the Daasanach Human Biology Project, an existing longitudinal study, to recruit 600 adults across approximately 450 households in 12 communities in Illeret Sub-County, Marsabit County, Kenya across six study waves. Data collection will occur seasonally during the wet (March-April) and dry (June-July) seasons. Household survey, anthropometric, dietary, doubly labeled water, point-of-care, lab-based biomarker, and water quality data will be collected to assess the impact of water salinity, heat stress, and other relevant exposures on health. Multi-level regression will be used to account for the longitudinal and nested nature of the data to determine how water salinity coupled with environmental exposures like heat impact hydration, kidney, and cardiometabolic function, and hypertension among Daasanach pastoralists. DISCUSSION: Exploring how water salinity in hot environments impacts human health can help uncover the environmental and social pathways to CKD and cardiovascular diseases facing populations around the world dealing with freshwater salinization. The data generated will provide dose-specific health standards for sodium-chloride in water.

Indexed as

Drinking WaterHeat-Shock ResponseHeat Stress DisordersHypertensionRenal Insufficiency, ChronicSalinityWater InsecurityAdultFemaleHumansKenyaLongitudinal StudiesDrinking Waterchronic kidney diseaseheathypertensionKenyawater salinity

Identifiers

PMID42865079
PMCPMC13659031

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.