ArticlePain research & management2026
Iron-Sensitive MRI Reveals Individual Differences in Pain Modulation Rather Than Categorical Markers in Chronic Pain and Migraine.
Article in Pain research & management, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Iron-Sensitive MRI Reveals Individual Differences in Pain Modulation Rather Than Categorical Markers in Chronic Pain and Migraine.Pain research & management · 2026Article
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Authors and funding
7 authors.
Funding
Abstract
objectiveTo determine whether regional iron levels are associated with endogenous pain-inhibitory function and whether iron-sensitive MRI techniques, quantitative magnetic susceptibility (QSM) and
methodsSixty participants (20 CP, 20 M, and 20 HV) underwent a 3T MRI examination. Pain modulatory and autonomic function was assessed using conditioned pain modulation (CPM) and pupil reflex dilation (PRD) across all participants (n = 60), whereas quantitative sensory testing (QST) and pain sensitivity questionnaire (PSQ) were assessed in CP and M only (n = 40). Group differences and iron-pain relationships were evaluated using ANOVA or Kruskal-Wallis tests and linear regression models.
resultsDistinct region- and modality-specific relationships were observed between iron-sensitive MRI measures and pain-related outcomes.
conclusionModality-specific associations between iron-sensitive MRI measures and descending inhibition, nociceptive gain, and autonomic reactivity were observed. These findings indicate that QSM and
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