ArticleAesthetic plastic surgery2026
Influence of Cannula Design on Lipoaspirate Architecture: A Double-Blind, Split-Body Trial Comparing Basket, Accelerator, and Candy Cane Cannulas.
Article in Aesthetic plastic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAutologous fat grafting is widely used in reconstructive and esthetic surgery; however, variability in graft retention remains a major limitation. Cannula design may influence the mechanical trauma inflicted during fat harvesting, potentially affecting adipocyte architecture and tissue integrity. This study aimed to evaluate the macroscopic and histologic characteristics of adipose tissue harvested using three different suction cannulas. MATERIALS AND
methodsA double-blind, non-randomized, split-body clinical trial was conducted. Adipose tissue was harvested from the abdominal region of sixteen patients undergoing elective liposuction using three 4-mm diameter cannulas (Basket, Accelerator [ACC], and Candy Cane). Lipoaspirate samples were processed to separate aqueous, adipose, and oily phases. Macroscopic parcel area was measured using stereoscopic imaging, and histologic evaluation assessed adipocyte alterations, septal connective tissue disorganization, and debris presence. Statistical analysis aimed to determine differences from each characteristic per cannula design.
resultsA total of 48 adipose tissue samples were analyzed. The ACC cannula produced the largest adipose parcels and exhibited greater parcel size heterogeneity, whereas the Candy Cane and Basket cannulas generated smaller and more uniform parcels. No significant differences were observed among cannula types in the proportions of aqueous, adipose, or oily phases. Histologic analysis showed no significant association between cannula type and adipocyte alterations, septal disorganization, or debris presence. Patient age demonstrated significant correlations with adipose-phase volume and parcel size across cannula types.
conclusionCannula geometry influences the macroscopic architecture of harvested adipose tissue but does not appear to significantly affect histologic integrity or phase distribution when standardized harvesting conditions are applied. Patient-related factors, particularly age, may contribute to variability in adipose tissue characteristics at the time of harvest. LEVEL OF EVIDENCE II: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
Indexed as
Identifiers
42864544What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.