ArticleSurgical endoscopy2026
Optimizing drain management following distal pancreatectomy: fewer drains and earlier removal guided by drain fluid amylase and C-reactive protein levels.
Article in Surgical endoscopy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAppropriate postoperative drain management, including early drain removal, is crucial following distal pancreatectomy (DP). This study aimed to investigate reliable criteria for early drain removal and the optimal drain placement site.
methodsWe retrospectively analyzed patients undergoing DP from 2014 to 2024, with drains placed at the pancreatic stump and/or the left subphrenic space. Short-term outcomes were compared according to clinically relevant postoperative pancreatic fistula (CR-POPF) occurrence, and the risk factors were identified.
resultsAmong 258 patients who underwent DP, 85.7% (n = 221) used two drains. CR-POPF developed in 28.3% (n = 73). The CR-POPF group demonstrated higher body mass index, less frequent minimally invasive surgery, greater blood loss, and more transfusions than the no CR-POPF group. The CR-POPF group exhibited significantly higher drain fluid amylase and C-reactive protein levels on postoperative days (POD) 1 and 3 (DFA1/3 and CRP1/3). Multivariable analysis identified DFA3 ≥ 1,000 U/L (odds ratio [OR] 8.21; P < 0.001), CRP3 ≥ 12 mg/dL (OR 3.37; P = 0.004), laparotomy (OR 3.26; P = 0.007), age (OR 1.04; P = 0.049), and operative time (OR 1.01; P = 0.006) as independent predictors for CR-POPF. The left subphrenic drain showed lower DFA1/3 values and a lesser association with CR-POPF than the pancreatic stump drain.
conclusionDFA3 and CRP3 may function as practical indicators for early drain removal. Left subphrenic drain may be considered for omission when an effective drain is placed at the pancreatic stump.
Indexed as
Identifiers
42864459What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.