Article in Nature neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
14 authors.
Han CaoDivision of Life Science, State Key Laboratory of Nervous System Disorders, Daniel and Mayce Yu Molecular Neuroscience Center, The Hong Kong University of Science and Technology, Hong Kong Special Administrative Region, China.ORCID http://orcid.org/0000-0001-9992-9108
Yifan FuDivision of Life Science, State Key Laboratory of Nervous System Disorders, Daniel and Mayce Yu Molecular Neuroscience Center, The Hong Kong University of Science and Technology, Hong Kong Special Administrative Region, China.ORCID http://orcid.org/0000-0003-4915-6260
Xiaopu ZhouDivision of Life Science, State Key Laboratory of Nervous System Disorders, Daniel and Mayce Yu Molecular Neuroscience Center, The Hong Kong University of Science and Technology, Hong Kong Special Administrative Region, China.ORCID http://orcid.org/0000-0001-5307-5805
Yangyang DuanDivision of Life Science, State Key Laboratory of Nervous System Disorders, Daniel and Mayce Yu Molecular Neuroscience Center, The Hong Kong University of Science and Technology, Hong Kong Special Administrative Region, China.ORCID http://orcid.org/0000-0002-0823-6574
Fanny C F IpDivision of Life Science, State Key Laboratory of Nervous System Disorders, Daniel and Mayce Yu Molecular Neuroscience Center, The Hong Kong University of Science and Technology, Hong Kong Special Administrative Region, China.ORCID http://orcid.org/0000-0001-5162-1761
Yu ChenDivision of Life Science, State Key Laboratory of Nervous System Disorders, Daniel and Mayce Yu Molecular Neuroscience Center, The Hong Kong University of Science and Technology, Hong Kong Special Administrative Region, China.
Shenyuan HuCenter for Stem Cell Research, HKUST-Nan Fung Life Sciences Joint Laboratory, The Hong Kong University of Science and Technology, Hong Kong Special Administrative Region, China.ORCID http://orcid.org/0000-0001-8528-592X
Timothy C Y KwokTherese Pei Fong Chow Research Centre for Prevention of Dementia, Division of Geriatrics, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.ORCID http://orcid.org/0000-0001-9253-3549
Kin Y MokDivision of Life Science, State Key Laboratory of Nervous System Disorders, Daniel and Mayce Yu Molecular Neuroscience Center, The Hong Kong University of Science and Technology, Hong Kong Special Administrative Region, China.
Tom H CheungDivision of Life Science, State Key Laboratory of Nervous System Disorders, Daniel and Mayce Yu Molecular Neuroscience Center, The Hong Kong University of Science and Technology, Hong Kong Special Administrative Region, China.ORCID http://orcid.org/0000-0003-0796-5406
John HardyInnoHK Hong Kong Center for Neurodegenerative Diseases, Hong Kong Special Administrative Region, China.
Amy K Y FuDivision of Life Science, State Key Laboratory of Nervous System Disorders, Daniel and Mayce Yu Molecular Neuroscience Center, The Hong Kong University of Science and Technology, Hong Kong Special Administrative Region, China. boamy@ust.hk.ORCID http://orcid.org/0000-0003-4085-6201
Nancy Y IpDivision of Life Science, State Key Laboratory of Nervous System Disorders, Daniel and Mayce Yu Molecular Neuroscience Center, The Hong Kong University of Science and Technology, Hong Kong Special Administrative Region, China. boip@ust.hk.ORCID http://orcid.org/0000-0002-2763-8907
Funding
Innovation and Technology Commission (ITF) InnoHK, ITCPD/17-9, ITS/207/18FP, MRP/042/18XResearch Grants Council, University Grants Committee (RGC, UGC) C6027-19GFResearch Grants Council, University Grants Committee (RGC, UGC) T13-605/18WUniversity Grants Committee (UGC) AoE/M-604/16
6 · The paper itself
Abstract
Although Alzheimer's disease (AD) has a polygenic architecture, with numerous associated single-nucleotide polymorphisms (SNPs) identified, the contribution of structural variants (SVs) is unclear. In this study, using long-read (n = 11) and short-read (n = 3,190) sequencing data from the Chinese population, we show that common SVs contribute to AD heritability beyond common SNPs. We identify an expanded CCG repeat in the FAM193B promoter that shows a genome-wide significant association with increased AD risk (odds ratio = 2.20 per 10-repeat increase, P = 5.5 × 10
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Genome-wide analysis of common structural variants in Alzheimer's disease identifies a risk-associated regulatory CCG repeat in FAM193B. · full record | OpenQuestion